%0 Journal Article
%A Hruby, Laura
%A Schaal, Katerina
%A Delaidelli, Alberto
%A Picard, Daniel Joseph
%A Dunham, Christopher
%A Lewandowska, Oksana
%A Reiff, Tobias
%A Larcher, Magalie
%A Pouponnot, Celio
%A Sorensen, Poul Hb
%A Rotblat, Barak
%A Reifenberger, Guido
%A Remke, Marc
%A Leprivier, Gabriel
%T The EIF4EBP1 gene encoding 4EBP1 is transcriptionally upregulated by MYC and linked to shorter survival in medulloblastoma.
%J Cell death discovery
%V 11
%N 1
%@ 2058-7716
%C London
%I Nature Publishing Group
%M DKFZ-2025-01439
%P 330
%D 2025
%X Medulloblastoma (MB) is the most common malignant brain tumor in childhood and is stratified into four molecular groups ‒ Wingless and Int-1 (WNT), Sonic hedgehog (SHH), Group 3 and Group 4. Group 3 MB patients exhibit the poorest prognosis, with a 5-year overall survival of <60
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:40670359
%2 pmc:PMC12267489
%R 10.1038/s41420-025-02601-x
%U https://inrepo02.dkfz.de/record/302992