%0 Journal Article
%A Mutemi, Kevin Nzumbi
%A Simakov, Oleg
%A Pan, Leslie
%A Santangeli, Luca
%A Null, Ryan Wesley
%A Handberg-Thorsager, Mette
%A Vellutini, Bruno Cossermelli
%A Peterson, Kevin J
%A Fromm, Bastian
%A Larsson, Tomas
%A Savage, Emily
%A Lopez, Mireia Osuna
%A Hercog, Rajna
%A Provaznik, Jan
%A Ordonez Rueda, Diana Angelica
%A Azevedo, Nayara
%A Gazave, Eve
%A Vervoort, Michel
%A Tomancak, Pavel
%A Tan, Wenhua
%A Winkler, Sylke
%A Benes, Vladimir
%A Hui, Jerome
%A Helm, Conrad
%A Özpolat, B Duygu
%A Arendt, Detlev
%T A genome resource for the marine annelid Platynereis spp.
%J BMC genomics
%V 26
%N 1
%@ 1471-2164
%C London
%I BioMed Central
%M DKFZ-2025-01464
%P 665
%D 2025
%X The marine annelid Platynereis dumerilii is a model organism used in many research areas including evolution and development, neurobiology, ecology and regeneration. Here we present the genomes of P. dumerilii (laboratory culture reference and a single individual assembly) and of the closely related P. massiliensis and P. megalops (single individual assembly) to facilitate comparative genomic approaches and help explore Platynereis biology. We used long-read sequencing technology and chromosomal-conformation capture along with extensive transcriptomic resources to obtain and annotate a draft genome assembly of   1.47 Gbp for P. dumerilii, of which more than half represent repeat elements. We predict around 29,000 protein-coding genes, with relatively large intron sizes, over 38,000 non-coding genes, and 105 miRNA loci. We further explore the high genetic variation (  3
%K Animals
%K Genome
%K Polychaeta: genetics
%K Genomics
%K Molecular Sequence Annotation
%K Annelida: genetics
%K Transcriptome
%K Platynereis (Other)
%K Platynereis dumerilii (Other)
%K Annelid (Other)
%K Evo-devo (Other)
%K Genome (Other)
%K Model organism (Other)
%K Spiralia (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:40660120
%2 pmc:PMC12257675
%R 10.1186/s12864-025-11727-2
%U https://inrepo02.dkfz.de/record/303017