TY  - JOUR
AU  - Mutemi, Kevin Nzumbi
AU  - Simakov, Oleg
AU  - Pan, Leslie
AU  - Santangeli, Luca
AU  - Null, Ryan Wesley
AU  - Handberg-Thorsager, Mette
AU  - Vellutini, Bruno Cossermelli
AU  - Peterson, Kevin J
AU  - Fromm, Bastian
AU  - Larsson, Tomas
AU  - Savage, Emily
AU  - Lopez, Mireia Osuna
AU  - Hercog, Rajna
AU  - Provaznik, Jan
AU  - Ordonez Rueda, Diana Angelica
AU  - Azevedo, Nayara
AU  - Gazave, Eve
AU  - Vervoort, Michel
AU  - Tomancak, Pavel
AU  - Tan, Wenhua
AU  - Winkler, Sylke
AU  - Benes, Vladimir
AU  - Hui, Jerome
AU  - Helm, Conrad
AU  - Özpolat, B Duygu
AU  - Arendt, Detlev
TI  - A genome resource for the marine annelid Platynereis spp.
JO  - BMC genomics
VL  - 26
IS  - 1
SN  - 1471-2164
CY  - London
PB  - BioMed Central
M1  - DKFZ-2025-01464
SP  - 665
PY  - 2025
AB  - The marine annelid Platynereis dumerilii is a model organism used in many research areas including evolution and development, neurobiology, ecology and regeneration. Here we present the genomes of P. dumerilii (laboratory culture reference and a single individual assembly) and of the closely related P. massiliensis and P. megalops (single individual assembly) to facilitate comparative genomic approaches and help explore Platynereis biology. We used long-read sequencing technology and chromosomal-conformation capture along with extensive transcriptomic resources to obtain and annotate a draft genome assembly of   1.47 Gbp for P. dumerilii, of which more than half represent repeat elements. We predict around 29,000 protein-coding genes, with relatively large intron sizes, over 38,000 non-coding genes, and 105 miRNA loci. We further explore the high genetic variation (  3
KW  - Animals
KW  - Genome
KW  - Polychaeta: genetics
KW  - Genomics
KW  - Molecular Sequence Annotation
KW  - Annelida: genetics
KW  - Transcriptome
KW  - Platynereis (Other)
KW  - Platynereis dumerilii (Other)
KW  - Annelid (Other)
KW  - Evo-devo (Other)
KW  - Genome (Other)
KW  - Model organism (Other)
KW  - Spiralia (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:40660120
C2  - pmc:PMC12257675
DO  - DOI:10.1186/s12864-025-11727-2
UR  - https://inrepo02.dkfz.de/record/303017
ER  -