TY  - JOUR
AU  - van den Bent, Martin J
AU  - Cloughesy, Timothy F
AU  - Ellingson, Benjamin M
AU  - Allen, Joshua E
AU  - Blackman, Samuel C
AU  - Kieran, Mark W
AU  - Tonn, Joerg C
AU  - Karschnia, Philipp
AU  - Wijnenga, Maarten
AU  - Pallud, Johan
AU  - Young, Robert J
AU  - Huang, Raymond Y
AU  - Mellinghoff, Ingo K
AU  - de Groot, John
AU  - van der Hoorn, Anouk
AU  - Youssef, Gilbert
AU  - Hervey-Jumper, Shawn L
AU  - Vogelbaum, Michael A
AU  - Chang, Susan M
AU  - Wen, Patrick Y
TI  - The Use of Minor Response, Volumetric Assessment and Growth Rate Kinetics as Endpoints in Grade 1-3 Glioma Clinical Trials: a RANO perspective.
JO  - Neuro-Oncology
VL  - nn
SN  - 1522-8517
CY  - Oxford
PB  - Oxford Univ. Press
M1  - DKFZ-2025-01483
SP  - nn
PY  - 2025
N1  - epub
AB  - The RANO criteria for response to treatment in glioma make a distinction between enhancing and unenhancing tumors, which reflects assessment of a different biological process underlying the MRI findings in enhancing and non-enhancing tumors. The recent regulatory approval of tovorafenib has also considered the patients with minor responses (25
KW  - Minor Response (Other)
KW  - RANO (Other)
KW  - Tumor Growth rate (Other)
KW  - unenhancing tumors (Other)
KW  - volumetric (3D) assessment (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:40692474
DO  - DOI:10.1093/neuonc/noaf173
UR  - https://inrepo02.dkfz.de/record/303036
ER  -