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@ARTICLE{Bing:303084,
author = {X. Bing and Q. Lei$^*$ and L. Wang and X. Zhao and X. Chen
and L. Zhang and A. Försti$^*$ and J. Yang and T. Chen},
title = {{A}ssessment of long-term survival in childhood cancer
patients using cancer registry data from eastern {C}hina:
{P}eriod analysis outperforms traditional analysis.},
journal = {International journal of cancer},
volume = {nn},
issn = {0020-7136},
address = {Bognor Regis},
publisher = {Wiley-Liss},
reportid = {DKFZ-2025-01509},
pages = {nn},
year = {2025},
note = {epub},
abstract = {This study systematically evaluated whether period analysis
outperforms traditional cohort and complete analyses in
estimating 5-year relative survival (RS) for childhood
cancer patients using data from nine cancer registries in
Taizhou, Eastern China (2009-2018). Analyses included
patients under 15 years diagnosed with childhood cancers,
with 5-year RS estimates from cohort, complete, and period
methods compared against observed actual survival
(2014-2018: $70.1\%).$ Accuracy and robustness were assessed
via deviation value (DV) and standard error (SE). Cohort
analysis yielded a 5-year RS of $55.8\%$ (DV: $-14.3\%,$ SE:
2.4), complete analysis $61.1\%$ (DV: $-9.0\%,$ SE: 1.7),
and period analysis $68.2\%$ (DV: $-1.9\%,$ SE: 2.1).
Stratified evaluations by sex, region, age at diagnosis, and
cancer types confirmed period analysis as the most accurate
(lowest DV across subgroups) while complete analysis showed
the smallest SE values, indicating superior robustness.
Cohort analysis performed the worst in both accuracy and
robustness. This study is the first in China to validate
that period analysis offers superior accuracy in estimating
5-year RS for childhood cancer patients overall and across
various stratifications compared to cohort and complete
analyses. Findings underscore the utility of period analysis
in generating timely survival estimates to inform early
detection strategies and cancer control policies, offering
critical methodological support for advancing pediatric
oncology outcomes assessment in China.},
keywords = {cancer registry (Other) / childhood cancers (Other) /
long‐term survival (Other) / period analysis (Other)},
cin = {C110 / B062 / HD01},
ddc = {610},
cid = {I:(DE-He78)C110-20160331 / I:(DE-He78)B062-20160331 /
I:(DE-He78)HD01-20160331},
pnm = {313 - Krebsrisikofaktoren und Prävention (POF4-313)},
pid = {G:(DE-HGF)POF4-313},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:40699182},
doi = {10.1002/ijc.70060},
url = {https://inrepo02.dkfz.de/record/303084},
}