TY  - JOUR
AU  - Linge, Annett
AU  - Ketzmerick, Carina
AU  - Gurtner, Kristin
AU  - Hoinkis, Cordelia
AU  - Löck, Steffen
AU  - Krause, Mechthild
TI  - Development of a model to guide the decision for radiotherapy in deep-inspiration breath-hold in patients with left-sided breast cancer.
JO  - Strahlentherapie und Onkologie
VL  - 202
IS  - 1
SN  - 0179-7158
CY  - Heidelberg
PB  - Springer Medizin
M1  - DKFZ-2025-01576
SP  - 23-29
PY  - 2026
N1  - 2026 Jan;202(1):23-29
AB  - Patients with left-sided breast cancer receiving radiotherapy are at risk of developing chronic cardiac toxicities. Cardiac dose-sparing techniques such as deep-inspiration breath-hold (DIBH) can reduce this risk. In this study, a model has been developed including tumor localization, left lung volume, and the distance between the heart and medial chest wall as well as age and Eastern Cooperative Oncology Group (ECOG) performance status, which may help to guide the decision for or against DIBH after planning computed tomography (CT) in free breathing directly before initiation of radiotherapy planning.
KW  - Cardiac toxicity (Other)
KW  - DIBH (Other)
KW  - Gating (Other)
KW  - Heart-sparing techniques (Other)
KW  - Irradiation (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:40728585
DO  - DOI:10.1007/s00066-025-02438-4
UR  - https://inrepo02.dkfz.de/record/303225
ER  -