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@ARTICLE{Jungert:303226,
      author       = {A. Jungert and A. Finze and A. Betzler and C. Reißfelder
                      and S. Blank and M. Otto and G. Vassilev and J. Betzler$^*$},
      title        = {{F}ood {T}olerance and {Q}uality of {E}ating {A}fter
                      {B}ariatric {S}urgery-{A}n {O}bservational {S}tudy of a
                      {G}erman {O}besity {C}enter.},
      journal      = {Journal of Clinical Medicine},
      volume       = {14},
      number       = {14},
      issn         = {2077-0383},
      address      = {Basel},
      publisher    = {MDPI},
      reportid     = {DKFZ-2025-01577},
      pages        = {4961},
      year         = {2025},
      note         = {#LA:B440#},
      abstract     = {Background: Bariatric surgeries, specifically laparoscopic
                      sleeve gastrectomy (SG) and Roux-en-Y gastric bypass (RYGB),
                      are a common intervention for morbid obesity, significantly
                      affecting food tolerance and quality of eating.
                      Understanding these changes is crucial for improving
                      postoperative care and long-term success. Methods: This
                      observational study at University Hospital Mannheim involved
                      91 patients, aged between 18 and 65 year, who underwent SG
                      or RYGB between 2009 and 2019. Food tolerance was assessed
                      between 25 days and 117 months after surgery using the
                      validated score by Suter et al. (Food Tolerance Score, FTS)
                      and an additional score evaluating tolerance to specific
                      food groups and quality of life. Data on body composition
                      were collected through Bioelectrical Impedance Analysis
                      (BIA) at follow-up visits. Statistical analyses included
                      linear mixed models to analyze the association of food
                      tolerance with body composition changes. Results: The FTS
                      indicated moderate or poor food tolerance in $62.6\%$ of
                      patients, with no significant differences between SG and
                      RYGB. Considering the results of the additional score, food
                      groups such as red meat, wheat products, raw vegetables,
                      carbon dioxide, fatty foods, convenience food, and sweets
                      were the most poorly tolerated food groups. A total of 57 of
                      the participants had a baseline and follow-up BIA
                      measurement. Postoperatively, a significant reduction in
                      body weight and BMI as well as in BIA parameters (fat mass,
                      lean mass, body cell mass, and phase angle) was found.
                      Quality of life improved after bariatric surgery and
                      $76.9\%$ rated their nutritional status as good or
                      excellent, despite possible food intolerances. Conclusions:
                      Bariatric surgery significantly reduces weight and alters
                      food tolerance. Despite moderate or poor food tolerance,
                      patients reported high satisfaction with their nutritional
                      status and quality of life. Detailed food tolerance
                      assessments and personalized dietary follow-ups are
                      essential for the early detection and management of
                      postoperative malnutrition, ensuring sustained weight loss
                      and improved health outcomes.},
      keywords     = {Roux-en-Y gastric bypass (Other) / bariatric surgery
                      (Other) / bioelectrical impedance analysis (Other) / food
                      tolerance (Other) / quality of life (Other) / sleeve
                      gastrectomy (Other)},
      cin          = {B440},
      ddc          = {610},
      cid          = {I:(DE-He78)B440-20160331},
      pnm          = {312 - Funktionelle und strukturelle Genomforschung
                      (POF4-312)},
      pid          = {G:(DE-HGF)POF4-312},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:40725653},
      doi          = {10.3390/jcm14144961},
      url          = {https://inrepo02.dkfz.de/record/303226},
}