TY - JOUR
AU - Shumilov, Evgenii
AU - Scholz, Julia Katharina
AU - Seib, Maximilian
AU - Mazzeo, Paolo
AU - Wurm-Kuczera, Rebecca
AU - Vucinic, Vladan
AU - Holtick, Udo
AU - Boyadzhiev, Hristo
AU - Melchardt, Thomas
AU - Hölscher, Alexander
AU - Schultze-Florey, Christian
AU - Abdelhafez, Atef
AU - Velazquez, Giuliano Filippini
AU - Ossami Saidy, Anna
AU - Lesan, Vadim
AU - Schnetzke, Ulf
AU - Kerkhoff, Andrea
AU - Bacher, Ulrike
AU - Ghandili, Susanne
AU - Aydilek, Enver
AU - Gebauer, Niklas
AU - Weber, Thomas
AU - Wulf, Gerald
AU - Glass, Bertram
AU - Thurner, Lorenz
AU - Heidel, Florian H
AU - Schmid, Christoph
AU - Viardot, Andreas
AU - Hänel, Mathias
AU - Dietrich, Sascha
AU - Pabst, Thomas
AU - Ayuk, Francis
AU - von Tresckow, Bastian
AU - Chapuy, Björn
AU - Pott, Christiane
AU - Müller, Fabian
AU - Lenz, Georg
TI - Outcomes of bispecific antibody therapy after CAR T-cell failure in relapsed/refractory large B-cell lymphoma.
JO - Blood advances
VL - 9
IS - 15
SN - 2473-9529
CY - Washington, DC
PB - American Society of Hematology
M1 - DKFZ-2025-01604
SP - 3955 - 3966
PY - 2025
AB - Patients with large B-cell lymphoma (LBCL) who experience relapsed disease after CD19-directed chimeric antigen receptor (CAR) T-cell (CAR-T) therapy have a poor prognosis. Bispecific antibodies (BsAbs) induce complete remissions in ∼35
KW - Humans
KW - Antibodies, Bispecific: therapeutic use
KW - Male
KW - Female
KW - Middle Aged
KW - Immunotherapy, Adoptive: methods
KW - Immunotherapy, Adoptive: adverse effects
KW - Aged
KW - Lymphoma, Large B-Cell, Diffuse: therapy
KW - Lymphoma, Large B-Cell, Diffuse: mortality
KW - Lymphoma, Large B-Cell, Diffuse: drug therapy
KW - Lymphoma, Large B-Cell, Diffuse: pathology
KW - Adult
KW - Recurrence
KW - Retrospective Studies
KW - Treatment Outcome
KW - Receptors, Chimeric Antigen
KW - Aged, 80 and over
KW - Antibodies, Bispecific (NLM Chemicals)
KW - Receptors, Chimeric Antigen (NLM Chemicals)
LB - PUB:(DE-HGF)16
C6 - pmid:40238938
DO - DOI:10.1182/bloodadvances.2024015719
UR - https://inrepo02.dkfz.de/record/303259
ER -