%0 Journal Article %A Degerli, Esra %A El-Marouk, Karim %A Käsmann, Lukas %A Khaltar, Khulangaa %A Mansoorian, Sina %A Richlitzki, Cedric %A Kauffmann-Guerrero, Diego %A Tufman, Amanda %A Reinmuth, Niels %A Duell, Thomas %A Schmidt-Hegemann, Nina-Sophie %A Manapov, Farkhad %A Belka, Claus %A Eze, Chukwuka %T Empiric stereotactic body radiotherapy for presumed early-stage lung cancer : Pulmonary function changes, treatment-related toxicity and survival outcome. %J Strahlentherapie und Onkologie %V nn %@ 0179-7158 %C Heidelberg %I Springer Medizin %M DKFZ-2025-01622 %P nn %D 2025 %Z epub %X Due to demographic shifts, the population is aging, and patients are experiencing more comorbidities. Stereotactic body radiotherapy (SBRT) offers high rates of local control for patients with medically inoperable early-stage non-small cell lung cancer (NSCLC). However, obtaining histopathological confirmation can be challenging due to severe comorbidities, small tumors, or unfavorable anatomical locations.Between 2011 and 2022, we retrospectively analyzed a cohort of patients who underwent lung SBRT for presumed early-stage NSCLC at our institution. Out of 486 consecutive patients treated during this period, 56 patients (11.5 %K Lung function (Other) %K Lung neoplasms (Other) %K Pathologic confirmation (Other) %K Radiographic (Other) %K Stereotactic ablative radiotherapy (SABR) (Other) %F PUB:(DE-HGF)16 %9 Journal Article %$ pmid:40760181 %R 10.1007/s00066-025-02434-8 %U https://inrepo02.dkfz.de/record/303373