TY  - JOUR
AU  - Rinne, Sanni
AU  - Michels, Birgitta
AU  - Butt, Julia
AU  - Syrjänen, Kari
AU  - Grenman, Seija
AU  - Waterboer, Tim
AU  - Syrjänen, Stina
AU  - Louvanto, Karolina
TI  - Epstein-Barr Virus Serology Associated With Persistent Oral Human Papillomavirus Infections in Men.
JO  - Journal of oral pathology & medicine
VL  - nn
SN  - 0300-9777
CY  - Oxford [u.a.]
PB  - Wiley-Blackwell
M1  - DKFZ-2025-01652
SP  - nn
PY  - 2025
N1  - epub
AB  - Most people acquire Epstein-Barr virus (EBV) and certain human papillomaviruses (HPVs) during their lifetime. HPV-related oropharyngeal carcinomas have increased in recent decades, particularly among men. The role of coinfection with viruses like EBV on HPV outcomes is unclear. We investigated potential associations between EBV serology and longitudinal outcomes of oral HPV infections in men.This study included 119 men from the Finnish Family HPV Study who were followed up for 3 years. Blood and oral cavity samples were collected at baseline, 12-, 24-, and 36-month follow-up visits. HPV was genotyped with the Multimetrix assay, and the serum IgG antibodies of EBV proteins Zebra, EA-D, EBNA, and VCAp18 were measured with fluorescent bead-based multiplex serology. Univariate regression analysis was used to measure the strength of the association between different variables.Most participants (99.2
KW  - EBV antibodies (Other)
KW  - EBV serology (Other)
KW  - Epstein–Barr virus (EBV) (Other)
KW  - human papillomavirus (HPV) (Other)
KW  - oral HPV infections (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:40772503
DO  - DOI:10.1111/jop.70015
UR  - https://inrepo02.dkfz.de/record/303427
ER  -