%0 Journal Article
%A Rinne, Sanni
%A Michels, Birgitta
%A Butt, Julia
%A Syrjänen, Kari
%A Grenman, Seija
%A Waterboer, Tim
%A Syrjänen, Stina
%A Louvanto, Karolina
%T Epstein-Barr virus (EBV) serology and its impact on oral human papillomavirus (HPV) infection outcomes in children during early childhood.
%J Microbiology spectrum
%V 13
%N 9
%@ 2165-0497
%C Birmingham, Ala.
%I ASM
%M DKFZ-2025-01670
%P e0007125
%D 2025
%Z 2025 Sep 2;13(9):e0007125
%X Epstein-Barr virus (EBV) and various human papillomaviruses (HPVs) commonly infect the oral mucosa, yet the longitudinal effects of these infections and their potential coinfections remain poorly understood. This study investigated whether early EBV infection and antibody responses influence oral HPV infections in young children. We included 283 children from the Finnish Family HPV cohort study, who were followed for 3 years post-birth. Oral and blood samples were collected at six time points (1, 2, 6, 12, 24, and 36 months). HPV genotyping was performed with Luminex and EBV-IgG antibodies to Zebra, early antigen-diffuse (EA-D), EBV nuclear antigen 1, and viral capsid antigen p18 with fluorescent bead-based multiplex serology. We noticed that most children (91.4
%K EBV serology (Other)
%K Epstein-Barr virus (Other)
%K children (Other)
%K human papillomavirus (Other)
%K oral HPV infection (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:40748074
%R 10.1128/spectrum.00071-25
%U https://inrepo02.dkfz.de/record/303473