TY  - JOUR
AU  - Blumenfeld, Philip
AU  - Pryanichnikov, Alexander
AU  - Hillman, Yair
AU  - Wajnryt, Ella
AU  - Berger, Aviad
AU  - Winograd, Shimshon
AU  - Wygoda, Marc
AU  - Salhab, Ayman
AU  - Fang, Marcel
AU  - Feldman, Jon
AU  - Popovtzer, Aron
TI  - Prospective clinical trial of upright image-guided proton therapy for locally recurrent head and neck and brain malignancies.
JO  - Radiotherapy and oncology
VL  - 211
SN  - 0167-8140
CY  - Amsterdam [u.a.]
PB  - Elsevier Science
M1  - DKFZ-2025-01690
SP  - 111097
PY  - 2025
N1  - #EA:E041# / Volume 211, October 2025, 111097
AB  - The advent of commercially available vertical CT systems has renewed interest in gantry-less proton therapy (PT), in which patients are treated in an upright position using a fixed beamline and robotic positioning. This study evaluates the feasibility, safety, and preliminary efficacy of novel gantry-less image-guided adaptive PT (IGAPT) for recurrent head and neck (HN) and brain malignancies.A planned interim analysis was performed on 20 adult patients with recurrent HN (80 
KW  - Adaptive radiotherapy (Other)
KW  - Image guidance (Other)
KW  - Proton therapy (Other)
KW  - Radiotherapy (Other)
KW  - Upright CT (Other)
KW  - Upright treatments (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:40803484
DO  - DOI:10.1016/j.radonc.2025.111097
UR  - https://inrepo02.dkfz.de/record/303499
ER  -