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@ARTICLE{Wang:303652,
      author       = {P. Wang and Y. Gao$^*$ and C. Chen and X. Zhao and Y. Zhang
                      and T. Liu and H. Jiang and Z. Wang and X. Zhao and J. Li},
      title        = {{FLASH} radiotherapy at a crossroads: a bibliometric
                      perspective on progress and challenges.},
      journal      = {Discover oncology},
      volume       = {16},
      number       = {1},
      issn         = {1868-8497},
      address      = {[New York]},
      publisher    = {Springer},
      reportid     = {DKFZ-2025-01716},
      pages        = {1570},
      year         = {2025},
      note         = {#EA:A430#},
      abstract     = {Flash radiotherapy (FLASH-RT), an emerging modality
                      utilizing ultra-high dose-rate (UHDR) irradiation (typically
                      > 40 Gy/s), has demonstrated a unique capacity to preserve
                      normal tissue integrity while maintaining tumor control
                      efficacy compared to conventional radiotherapy. Despite
                      exponential growth in FLASH-RT research over the past
                      decade, its scientific landscape has not yet been
                      systematically characterized through bibliometric analysis.
                      This study only includes articles from the Web of Science
                      Core Collection (WoSCC) and is limited to English-language
                      publications, which may introduce database and language
                      biases.Relevant articles and reviews on FLASH-RT were
                      retrieved from the WoSCC database. Bibliometric analysis and
                      scientific knowledge mapping were performed using the R
                      packages Bibliometrix, CiteSpace, and VOSviewer, in
                      conjunction with the online analytical tools provided by Web
                      of Science (WoS).A total of 572 publications from 2013 to
                      2025, spanning 179 countries/regions and involving 2,049
                      institutions, were analyzed. The United States, Switzerland,
                      and China were the leading contributors. The University of
                      Lausanne had the highest research output. These publications
                      appeared in 96 different journals, with Medical Physics
                      contributing the most studies. Among 2995 authors, Vozenin
                      MC had the highest publication count and H-index, while
                      Favaudon V's papers received the most citations. Frequent
                      keywords included irradiation, flash radiotherapy, radiation
                      therapy, and cells. Keyword clustering revealed eleven major
                      research directions, primarily focusing on pencil beam
                      scanning and dosimetry.This first bibliometric analysis of
                      FLASH-RT research highlights key trends, influential
                      contributors, and challenges. These findings provide
                      valuable insights into research frontiers and hotspots,
                      guiding future studies and collaborations.},
      keywords     = {Bibliometric analysis (Other) / CiteSpace (Other) / FLASH
                      radiotherapy (Other) / Ultra-high dose-rate (Other) /
                      VOSviewer (Other) / Web of science (Other)},
      cin          = {A430},
      ddc          = {610},
      cid          = {I:(DE-He78)A430-20160331},
      pnm          = {311 - Zellbiologie und Tumorbiologie (POF4-311)},
      pid          = {G:(DE-HGF)POF4-311},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:40819335},
      doi          = {10.1007/s12672-025-03400-7},
      url          = {https://inrepo02.dkfz.de/record/303652},
}