%0 Journal Article
%A Lehtinen, Tuomas
%A Zhang, Luayo
%A Sundquist, Kristina
%A Sundquist, Jan
%A Waterboer, Tim
%A Lehtinen, Matti Osmo Antero
%A Hemminki, Kari
%T Elevated Risk of HPV-Associated Oropharyngeal Cancers in Husbands of Women With Anogenital Cancer.
%J Cancer reports
%V 8
%N 9
%@ 2573-8348
%C Medford, MA
%I Wiley
%M DKFZ-2025-01801
%P e70333
%D 2025
%Z Z999
%X Human papillomavirus (HPV) infection is associated with tonsillar and base-of-tongue squamous cell carcinomas (TSCC/BOTSCC). We evaluated the relative risk (RR) of TSCC/BOTSCC in the husbands of women with anogenital cancer using the Swedish family database.The Swedish family database includes 3.5 million families and 16 million individuals identified since 1932 and linked to cancer data from 1958 to 2015. We explored the RR of TSCC/BOTSCC in husbands of women diagnosed with anogenital (anal, vulvar/vaginal, cervical) cancer or cervical carcinoma in situ (CIS) as compared to husbands of controls.The RR of TSCC/BOTSCC in husbands of women with invasive anogenital cancer increased by calendar time and decreasing ages at diagnoses. In 2002-2015, the RR peaked at 5.35 (95
%K Humans
%K Female
%K Papillomavirus Infections: virology
%K Papillomavirus Infections: complications
%K Papillomavirus Infections: epidemiology
%K Middle Aged
%K Sweden: epidemiology
%K Spouses: statistics & numerical data
%K Male
%K Adult
%K Anus Neoplasms: virology
%K Anus Neoplasms: epidemiology
%K Oropharyngeal Neoplasms: virology
%K Oropharyngeal Neoplasms: epidemiology
%K Aged
%K Vulvar Neoplasms: virology
%K Vulvar Neoplasms: epidemiology
%K Risk Factors
%K Uterine Cervical Neoplasms: virology
%K Uterine Cervical Neoplasms: epidemiology
%K Carcinoma, Squamous Cell: virology
%K Carcinoma, Squamous Cell: epidemiology
%K Papillomaviridae: isolation & purification
%K familial cancer (Other)
%K head and neck cancer (Other)
%K viral infection (Other)
%K viral oncology (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:40877205
%R 10.1002/cnr2.70333
%U https://inrepo02.dkfz.de/record/304247