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@ARTICLE{Ksmann:304248,
      author       = {L. Käsmann$^*$ and R. Gurtner and R. Rennollet and J.
                      Büntzel and O. Micke and C. Belka$^*$ and M. Pazos and R.
                      Mücke and J. Rauch and J. Hübner},
      title        = {{C}omplementary and {A}lternative {M}edicine ({CAM}) {U}se
                      in {P}atients {U}ndergoing {R}adiotherapy: {S}ex-specific
                      {P}revalence and {A}ssociations of {U}se {B}ased on the {S}3
                      {G}uideline {C}omplementary {M}edicine in {O}ncology
                      {Q}uestionnaire.},
      journal      = {In vivo},
      volume       = {39},
      number       = {5},
      issn         = {0258-851X},
      address      = {Kapandriti, Attiki},
      publisher    = {IIAR},
      reportid     = {DKFZ-2025-01802},
      pages        = {2969 - 2975},
      year         = {2025},
      abstract     = {This study aimed to assess the sex-specific prevalence and
                      patterns of complementary and alternative medicine (CAM) use
                      in patients undergoing radiotherapy, using the standardized
                      questionnaire developed as part of the S3 Guideline on
                      Complementary Medicine in Oncology.Between August and
                      December 2022, 112 out of 697 eligible cancer patients
                      receiving radiotherapy were prospectively enrolled and
                      completed a structured questionnaire assessing CAM use. The
                      questionnaire included 38 CAM methods classified according
                      to their potential for interactions.Female participants
                      generally used more CAM methods than male participants
                      (median methods: 3 vs. 1, p<0.001). The most frequently used
                      CAM methods were vitamin D $(46.4\%),$ sports/exercise
                      $(33\%)$ and vitamin A/C/E or beta-carotene $(25\%).$ At
                      least one of the listed CAM methods was used by $79.5\%.$ At
                      least three of the listed CAM methods were used by 52
                      $(46.4\%)$ patients. Thirty-six $(32.1\%)$ and 54 $(48.2\%)$
                      patients used CAM methods with known or potential
                      interactions, while 76 $(67.9\%)$ used methods with no known
                      interactions. In addition, a higher number of female
                      patients used uncertain methods or medications compared to
                      males (p=0.022). The desire for counseling was very similar
                      between both sexes, with no significant difference
                      (p=0.973).The high rate of CAM utility before radiotherapy,
                      especially among females, and the use of uncertain methods,
                      highlights the need for standardized questionnaires to
                      identify potential interactions. This would help enhance
                      patient safety through structured screening and counseling.},
      keywords     = {Humans / Complementary Therapies: methods / Complementary
                      Therapies: statistics $\&$ numerical data / Male / Female /
                      Surveys and Questionnaires / Middle Aged / Neoplasms:
                      radiotherapy / Neoplasms: epidemiology / Aged / Adult /
                      Prevalence / Sex Factors / Radiotherapy: methods /
                      Complementary and alternative medicine (Other) / cancer care
                      (Other) / interactions (Other) / patient-physician
                      communication (Other)},
      cin          = {MU01},
      ddc          = {610},
      cid          = {I:(DE-He78)MU01-20160331},
      pnm          = {899 - ohne Topic (POF4-899)},
      pid          = {G:(DE-HGF)POF4-899},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:40877141},
      doi          = {10.21873/invivo.14097},
      url          = {https://inrepo02.dkfz.de/record/304248},
}