%0 Journal Article
%A Tetzlaff, Fabian
%A Barnes, Benjamin
%A Jansen, Lina
%A Peters, Frederik
%A Schultz, Annemarie
%A Katalinic, Alexander
%A Kraywinkel, Klaus
%A Michalski, Niels
%A Nowossadeck, Enno
%A Hoebel, Jens
%T Widening socioeconomic inequalities in cancer incidence and related potential to reduce cancer between 2008 and 2019 in Germany.
%J Scientific reports
%V 15
%N 1
%@ 2045-2322
%C [London]
%I Springer Nature
%M DKFZ-2025-01827
%P 32232
%D 2025
%X Background Cancer is one of the main causes of a high burden of disease and one of the strongest contributors to earlier mortality among lower socioeconomic groups in Germany. Therefore, studying socio-economic inequalities in cancer incidence is of high relevance from a public-health and health-equity lens. The aim of this study was to examine in more depth time trends in socioeconomic inequalities in cancer incidence and the related potential for reducing the incidence of specific cancers across Germany. Methods We used epidemiologic data from the Centre for Cancer Registry Data at the Robert Koch Institute and official population statistics for Germany from 2008 to 2019. To analyse trends in socioeconomic inequalities in cancer incidence, we used an ecological study design and linked the cancer registry and population data with the German Index of Socioeconomic Deprivation at district level. We calculated standardised cancer incidence rates for the most common cancers by area-level socioeconomic deprivation and estimated the Slope and Relative Index of Inequality (SII, RII) to determine the extent of area-level socioeconomic inequalities in the risk of cancer. In a what-if analysis, counterfactual scenarios were used to calculate how much lower cancer incidence could be if socioeconomic inequalities in incidence were reduced or eliminated. Results Due to less favourable trends of cancer incidence in more deprived areas, socioeconomic inequalities in cancer incidence has widened to the detriment of residents in highly deprived areas. This was observed for all cancers combined and for several common cancers such as stomach, colorectal and lung cancer among both women and men. In 2017-19, total cancer incidence was 18
%K Humans
%K Germany: epidemiology
%K Neoplasms: epidemiology
%K Incidence
%K Female
%K Male
%K Socioeconomic Factors
%K Registries
%K Middle Aged
%K Aged
%K Adult
%K Health Status Disparities
%K Area-level socioeconomic inequalities (Other)
%K Deprivation (Other)
%K GISD (Other)
%K Germany (Other)
%K Social determinants (Other)
%K Trends cancer incidence (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:40890381
%R 10.1038/s41598-025-17859-5
%U https://inrepo02.dkfz.de/record/304287