000304300 001__ 304300 000304300 005__ 20250907022527.0 000304300 0247_ $$2doi$$a10.1158/1078-0432.CCR-24-3860 000304300 0247_ $$2pmid$$apmid:40560659 000304300 0247_ $$2ISSN$$a1078-0432 000304300 0247_ $$2ISSN$$a1557-3265 000304300 0247_ $$2altmetric$$aaltmetric:179097620 000304300 037__ $$aDKFZ-2025-01836 000304300 041__ $$aEnglish 000304300 082__ $$a610 000304300 1001_ $$00000-0001-7088-8146$$aWasserman, Jonathan D$$b0 000304300 245__ $$aUpdated Recommendations for Pediatric Surveillance in Hereditary Endocrine Neoplasia Syndromes: Multiple Endocrine Neoplasias, Hyperparathyroidism-Jaw Tumor Syndrome, and Carney Complex. 000304300 260__ $$aPhiladelphia, Pa. [u.a.]$$bAACR$$c2025 000304300 3367_ $$2DRIVER$$aarticle 000304300 3367_ $$2DataCite$$aOutput Types/Journal article 000304300 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1756967815_27123$$xReview Article 000304300 3367_ $$2BibTeX$$aARTICLE 000304300 3367_ $$2ORCID$$aJOURNAL_ARTICLE 000304300 3367_ $$00$$2EndNote$$aJournal Article 000304300 520__ $$aHereditary endocrine neoplasia syndromes comprise multiple entities associated with an increased risk for the development of endocrine and nonendocrine neoplasms and other systemic manifestations. These syndromes typically demonstrate autosomal dominant inheritance, and each syndrome is associated with a unique genetic predisposition to a distinct spectrum of tumor susceptibility. Moreover, genotype-phenotype associations within each syndrome may affect the spectrum, penetrance, and age of onset of associated tumors. As many endocrine tumors are benign and/or indolent, a careful approach to monitoring is necessary, wherein the nature, timing of initiation, and frequency of presymptomatic surveillance balance the goal of detecting tumors at a point in which intervention would limit tumor-associated morbidity against the physical, emotional, and financial burdens of surveillance. In this study, we summarize changes in knowledge and practice recommendations related to children with multiple endocrine neoplasia syndromes (types 1, 2A, 2B, 4, and 5), hyperparathyroidism-jaw tumor syndrome, and Carney complex since an initial summary in 2017. These updates reflect the evolving understanding of these complex genetic disorders and aim to improve patient care and outcomes. 000304300 536__ $$0G:(DE-HGF)POF4-312$$a312 - Funktionelle und strukturelle Genomforschung (POF4-312)$$cPOF4-312$$fPOF IV$$x0 000304300 588__ $$aDataset connected to CrossRef, PubMed, , Journals: inrepo02.dkfz.de 000304300 650_2 $$2MeSH$$aHumans 000304300 650_2 $$2MeSH$$aMultiple Endocrine Neoplasia: diagnosis 000304300 650_2 $$2MeSH$$aMultiple Endocrine Neoplasia: genetics 000304300 650_2 $$2MeSH$$aMultiple Endocrine Neoplasia: epidemiology 000304300 650_2 $$2MeSH$$aCarney Complex: diagnosis 000304300 650_2 $$2MeSH$$aCarney Complex: genetics 000304300 650_2 $$2MeSH$$aCarney Complex: epidemiology 000304300 650_2 $$2MeSH$$aChild 000304300 650_2 $$2MeSH$$aGenetic Predisposition to Disease 000304300 650_2 $$2MeSH$$aJaw Neoplasms: diagnosis 000304300 650_2 $$2MeSH$$aJaw Neoplasms: genetics 000304300 650_2 $$2MeSH$$aHyperparathyroidism: diagnosis 000304300 650_2 $$2MeSH$$aHyperparathyroidism: genetics 000304300 7001_ $$00000-0003-0865-8010$$aSchneider, Kami Wolfe$$b1 000304300 7001_ $$00000-0001-6894-1219$$aAchatz, Maria-Isabel$$b2 000304300 7001_ $$00000-0001-5394-8194$$aNakano, Yoshiko$$b3 000304300 7001_ $$00000-0003-0970-1850$$aZelley, Kristin$$b4 000304300 7001_ $$00000-0003-0039-3652$$aGallinger, Bailey$$b5 000304300 7001_ $$00000-0002-3952-881X$$aBauer, Andrew J$$b6 000304300 7001_ $$00000-0002-1935-5157$$aBecktell, Kerri D$$b7 000304300 7001_ $$00000-0003-0894-9301$$aWassner, Ari J$$b8 000304300 7001_ $$00009-0000-8270-8894$$aRaiti, Laura$$b9 000304300 7001_ $$00000-0003-3202-0447$$aDoria, Andrea S$$b10 000304300 7001_ $$00000-0003-0260-3975$$aStates, Lisa J$$b11 000304300 7001_ $$00000-0002-4058-5520$$aStratakis, Constantine A$$b12 000304300 7001_ $$00000-0002-6721-122X$$aBrodeur, Garrett M$$b13 000304300 7001_ $$00000-0002-4073-5509$$aDiller, Lisa R$$b14 000304300 7001_ $$00000-0002-2852-7387$$aKamihara, Junne$$b15 000304300 7001_ $$00000-0001-5752-9763$$aMalkin, David$$b16 000304300 7001_ $$0P:(DE-He78)a7c1bbac024fa232d9c6b78443328d9d$$aPajtler, Kristian$$b17$$udkfz 000304300 7001_ $$00000-0002-7496-4289$$aTamura, Chieko$$b18 000304300 7001_ $$00000-0003-3283-2197$$aVillani, Anita$$b19 000304300 7001_ $$00000-0003-0986-5476$$aWidjaja, Elysa$$b20 000304300 7001_ $$00000-0001-7653-9529$$aDas, Anirban$$b21 000304300 7001_ $$00000-0001-8333-0758$$aRednam, Surya P$$b22 000304300 773__ $$0PERI:(DE-600)2036787-9$$a10.1158/1078-0432.CCR-24-3860$$gVol. 31, no. 17, p. 3628 - 3637$$n17$$p3628 - 3637$$tClinical cancer research$$v31$$x1078-0432$$y2025 000304300 909CO $$ooai:inrepo02.dkfz.de:304300$$pVDB 000304300 9101_ $$0I:(DE-588b)2036810-0$$6P:(DE-He78)a7c1bbac024fa232d9c6b78443328d9d$$aDeutsches Krebsforschungszentrum$$b17$$kDKFZ 000304300 9131_ $$0G:(DE-HGF)POF4-312$$1G:(DE-HGF)POF4-310$$2G:(DE-HGF)POF4-300$$3G:(DE-HGF)POF4$$4G:(DE-HGF)POF$$aDE-HGF$$bGesundheit$$lKrebsforschung$$vFunktionelle und strukturelle Genomforschung$$x0 000304300 9141_ $$y2025 000304300 915__ $$0StatID:(DE-HGF)0100$$2StatID$$aJCR$$bCLIN CANCER RES : 2022$$d2024-12-27 000304300 915__ $$0StatID:(DE-HGF)0200$$2StatID$$aDBCoverage$$bSCOPUS$$d2024-12-27 000304300 915__ $$0StatID:(DE-HGF)0300$$2StatID$$aDBCoverage$$bMedline$$d2024-12-27 000304300 915__ $$0StatID:(DE-HGF)0199$$2StatID$$aDBCoverage$$bClarivate Analytics Master Journal List$$d2024-12-27 000304300 915__ $$0StatID:(DE-HGF)1050$$2StatID$$aDBCoverage$$bBIOSIS Previews$$d2024-12-27 000304300 915__ $$0StatID:(DE-HGF)0160$$2StatID$$aDBCoverage$$bEssential Science Indicators$$d2024-12-27 000304300 915__ $$0StatID:(DE-HGF)1190$$2StatID$$aDBCoverage$$bBiological Abstracts$$d2024-12-27 000304300 915__ $$0StatID:(DE-HGF)1110$$2StatID$$aDBCoverage$$bCurrent Contents - Clinical Medicine$$d2024-12-27 000304300 915__ $$0StatID:(DE-HGF)0113$$2StatID$$aWoS$$bScience Citation Index Expanded$$d2024-12-27 000304300 915__ $$0StatID:(DE-HGF)0150$$2StatID$$aDBCoverage$$bWeb of Science Core Collection$$d2024-12-27 000304300 915__ $$0StatID:(DE-HGF)9910$$2StatID$$aIF >= 10$$bCLIN CANCER RES : 2022$$d2024-12-27 000304300 9201_ $$0I:(DE-He78)B062-20160331$$kB062$$lB062 Pädiatrische Neuroonkologie$$x0 000304300 9201_ $$0I:(DE-He78)HD01-20160331$$kHD01$$lDKTK HD zentral$$x1 000304300 980__ $$ajournal 000304300 980__ $$aVDB 000304300 980__ $$aI:(DE-He78)B062-20160331 000304300 980__ $$aI:(DE-He78)HD01-20160331 000304300 980__ $$aUNRESTRICTED