TY  - JOUR
AU  - Renovanz, Mirjam
AU  - Hippler, Melina
AU  - Kuchen, Robert
AU  - Doerner, Lorenz
AU  - Rieger, David
AU  - Steinbach, Joachim P
AU  - Ronellenfitsch, Michael W
AU  - Voss, Martin
AU  - Kessler, Almuth F
AU  - Nickl, Vera
AU  - Misch, Martin
AU  - Onken, Julia Sophie
AU  - Rapp, Marion
AU  - Nadji-Ohl, Minou
AU  - Mehlitz, Marcus
AU  - Meixensberger, Jürgen
AU  - Fehrenbach, Michael Karl
AU  - Keric, Naureen
AU  - Ringel, Florian
AU  - Coburger, Jan
AU  - Lucas, Carolin Weiß
AU  - Wehinger, Jens
AU  - Schmidt-Graf, Friederike
AU  - Gempt, Jens
AU  - Tatagiba, Marcos
AU  - Tabatabai, Ghazaleh
AU  - Schranz, Melanie
AU  - Singer, Susanne
TI  - Physician-led versus questionnaire-based psychosocial screening in adults with high-grade glioma: a cluster-randomized controlled trial (GLIOPT).
JO  - Journal of neuro-oncology
VL  - nn
SN  - 0167-594X
CY  - Dordrecht [u.a.]
PB  - Springer Science + Business Media B.V
M1  - DKFZ-2025-01883
SP  - nn
PY  - 2025
N1  - epub
AB  - Patients diagnosed with high-grade gliomas (HGG) often experience substantial psychosocial dis-tress. However, due to neurological and neurocognitive deficits its assessment remains challenging, and needs remain unmet. We compared a novel face-to-face assessment during doctor-patient conversations with questionnaire-based screening.In this multicenter, two-arm cluster-randomized study involving 13 centers patients in the interven-tion group (IG) were screened for distress via physician-patient conversations, while the control group (CG) completed the Distress Thermometer. Primary outcome was the proportion of patients with poor emotional functioning (measured with the EORTC Quality of Life Questionnaire) who received specialized psychosocial care (PC) within 3 months. Data were collected via patient and physician reports and medical records. Analysis employed mixed models logistic regression.In total, 763 patients were enrolled at baseline, and 506 completed the follow-up. The emotional functioning was poor in 302/506 (59.7
KW  - Assessment (Other)
KW  - Distress (Other)
KW  - High-grade glioma (Other)
KW  - Primary brain tumor patients (Other)
KW  - Psychosocial burden (Other)
KW  - Psychosocial care (Other)
KW  - Screening (Other)
KW  - Supportive care needs (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:40931258
DO  - DOI:10.1007/s11060-025-05223-6
UR  - https://inrepo02.dkfz.de/record/304494
ER  -