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@ARTICLE{Walther:304589,
author = {G. Walther and T. Brand and N. Dragano and C. Meinke-Franze
and A. Führer and K.-H. Greiser$^*$ and O. Hovadorvska and
J. Kiekert and L. Krist and M. Leitzmann and W. Lieb and R.
Mikolajczyk and U. Mons$^*$ and F. Niedermayer and N. Obi
and C. Övermöhle and M. Reuter and B. Schmidt and I. M.
Velásquez and H. Völzke and K. Wirkner and H. Zeeb and T.
Bärninghausen and B. Fischer and L. Koch-Gallenkamp$^*$ and
V. Harth and A. Karch and B. Lange and A. Peters and T.
Pischon and H. Teismann and H. Becher and V. Winkler},
title = {{M}igration and {C}ardiovascular {D}isease: {A}
{C}omparative {S}tudy of {P}revalence and {R}isk {F}actor
{P}rofiles in {R}esettlers from the {G}erman {N}ational
{C}ohort ({NAKO}).},
journal = {Annals of epidemiology},
volume = {nn},
issn = {1047-2797},
address = {Amsterdam [u.a.]},
publisher = {Elsevier Science},
reportid = {DKFZ-2025-01912},
pages = {nn},
year = {2025},
note = {epub},
abstract = {Resettlers from the former Soviet Union are one of the
largest migrant groups in Germany. Previous studies found
lower cardiovascular disease (CVD) mortality among
resettlers compared to Germans without migration background
(autochthonous). Other studies have shown a higher
prevalence of CVD risk factors among resettlers, suggesting
a higher CVD mortality. The German National Cohort (NAKO)
provides an opportunity to explore these discrepancies.This
study used baseline data from NAKO and compared age-adjusted
percentages of self-reported CVD and associated risk factors
between the two groups. Logistic regression models estimated
adjusted odds ratios (OR) for associations between resettler
status and outcomes.Among 204,751 participants aged 19-75,
3,580 were resettlers and 169,538 autochthonous Germans.
Male resettlers had lower odds of risky alcohol consumption
(OR: 0.55; $95\%CI:$ 0.49-0.63) but higher odds of ever
smoking (OR: 1.26; $95\%CI:$ 1.13-1.41) compared to
autochthonous German men. Female resettlers showed higher
prevalence of hypertension, diabetes mellitus, obesity, and
elevated cholesterol/triglycerides, but lower prevalence of
risky alcohol consumption and smoking. In men, the odds of
peripheral artery disease (PAD) (OR: 0.46; $95\%CI:$
0.21-0.97) and any CVD (OR: 0.81; $95\%CI:$ 0.66-0.98) were
lower among resettlers. No other notable differences in
clinical CVDs were observed in men.Resettlers showed
differences regarding CVD risk factor distribution compared
to autochthonous Germans. These differences appear to
balance out, leading to similar overall CVD prevalence,
except for a lower prevalence of PAD and total CVD in male
resettlers. Future longitudinal data will allow to explore
long-term CVD trajectories.We compared the prevalence of
cardiovascular diseases (CVD) in a special group of migrants
(resettlers from the former Soviet Union; German:
(Spät-)Aussiedler) and autochthonous Germans, using data
from the German National Cohort (NAKO) and investigated risk
factors frequencies for these diseases in both groups. We
found that male resettlers had less of risky alcohol
consumption but smoked more than autochthonous German men.
Female resettlers showed higher prevalence of hypertension,
diabetes mellitus, obesity, and elevated cholesterol and
triglyceride levels, but lower prevalence of risky alcohol
consumption and smoking. The prevalence of most CVDs was
similar in both groups, except of peripheral artery disease
and all CVDs combined which we found less frequent in male
resettlers.},
keywords = {Cardiovascular diseases (CVDs) (Other) / German National
Cohort (NAKO) (Other) / Migrant health (Other) / Resettlers
(Other) / cardiovascular Risk factors (Other)},
cin = {C020 / C120 / C070},
ddc = {610},
cid = {I:(DE-He78)C020-20160331 / I:(DE-He78)C120-20160331 /
I:(DE-He78)C070-20160331},
pnm = {313 - Krebsrisikofaktoren und Prävention (POF4-313)},
pid = {G:(DE-HGF)POF4-313},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:40946730},
doi = {10.1016/j.annepidem.2025.09.008},
url = {https://inrepo02.dkfz.de/record/304589},
}