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@ARTICLE{Biswas:304985,
      author       = {D. Biswas and S. V. Shenoy and A. Chauhan and A. Halder and
                      A. Padhye and S. Dutta and S. Auromahima and H. Bavaskar and
                      D. Yadav and B. Ghosh$^*$ and S. Sasmal and N. Kumari and T.
                      R. Kumar and A. P. Mukherjee and S. Srivastava},
      title        = {{B}rain{P}rot v3.0: {A}n {I}ntegrative and {S}implified
                      {O}mics-{B}ased {K}nowledge-{B}ase {A}bout the {H}uman
                      {B}rain and {I}ts {A}ssociated {D}iseases.},
      journal      = {Journal of proteome research},
      volume       = {24},
      number       = {11},
      issn         = {1535-3893},
      address      = {Washington, DC},
      publisher    = {ACS Publications},
      reportid     = {DKFZ-2025-01976},
      pages        = {5352-5369},
      year         = {2025},
      note         = {2025 Nov 7;24(11):5352-5369},
      abstract     = {The advancements in neuroscience research and omics
                      technologies generate extensive data for brain-related
                      diseases and disorders that are scattered across various
                      manuscript repositories and databases, potentially hindering
                      global initiatives to advance neuroscience research. This
                      study introduces BrainProt v3.0
                      (https://www.brainprot.org/), an omics-driven knowledge-base
                      of human brain and associated diseases. BrainProt version
                      3.0 navigates the Human Brain Disease Atlas (HBDA) and
                      integrates the Brain Disease Marker Curator (BDMC) and Brain
                      Disease Drug Finder (BDDF). It features 20,202
                      disease-associated genes, 136,557 chemical target
                      interactions, and 2,145 clinical trial details.
                      Additionally, the Brain Disease Transcriptome Map (BDTM) and
                      Brain Disease Proteome Map (BDPM) collate multiomics data
                      from the most significant brain diseases, displaying an
                      expression profile across 52 datasets and 1,868 samples.
                      This platform also facilitates the exploration of biological
                      cross-talk and correlations between transcriptomics and
                      proteomics data to identify critical disease-associated
                      markers. In conclusion, BrainProt is designed to advance the
                      Human Brain Proteome Project (HBPP) by expanding the
                      integration of diseases and datasets, thereby elucidating
                      the complexities of brain diseases and enhancing the
                      research on the interplay between brain tumors and
                      neurodegenerative disorders.},
      keywords     = {biomarkers (Other) / brain tumors (Other) / clinical trials
                      (Other) / human brain (Other) / neurodegenerative diseases
                      (Other) / proteomics (Other) / transcriptomics (Other)},
      cin          = {A190},
      ddc          = {540},
      cid          = {I:(DE-He78)A190-20160331},
      pnm          = {311 - Zellbiologie und Tumorbiologie (POF4-311)},
      pid          = {G:(DE-HGF)POF4-311},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:41002257},
      doi          = {10.1021/acs.jproteome.4c00982},
      url          = {https://inrepo02.dkfz.de/record/304985},
}