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@ARTICLE{Egger:305028,
      author       = {N. Egger and L. Ruck and S. Nagelstraßer and J. Schirmer
                      and S. Wildenberg and A. Bitz and J. Herrler and S.
                      Schmitter$^*$ and M. Uder and A. Nagel$^*$},
      title        = {{E}valuation of an interleaved acquisition scheme for
                      improved robustness of channel-wise relative {B}1 + mapping
                      at 7 {T}.},
      journal      = {Magnetic resonance in medicine},
      volume       = {nn},
      issn         = {1522-2594},
      address      = {New York, NY [u.a.]},
      publisher    = {Wiley-Liss},
      reportid     = {DKFZ-2025-02010},
      pages        = {nn},
      year         = {2025},
      note         = {#LA:E020#/ epub},
      abstract     = {The purpose was to evaluate, whether an interleaved
                      acquisition scheme for a fast relative B 1 + $$
                      {\mathrm{B}}_1^{+} $$ mapping method at 7 T reduces the
                      likelihood of errors from exceeding the linear flip angle
                      (FA) regime compared to a conventional sequential
                      acquisition.Simulations of a channel-wise relative B 1 + $$
                      {\mathrm{B}}_1^{+} $$ mapping sequence were performed for
                      sequential and interleaved acquisition schemes at different
                      reference voltages (≙ different FAs). The simulations were
                      performed for a phantom, the heart and the prostate and were
                      based on 7 T ground-truth (GT) B 1 + $$ {\mathrm{B}}_1^{+}
                      $$ data acquired with an actual FA imaging sequence
                      (phantom) or obtained from electromagnetic field simulations
                      (heart/prostate). Acquisition schemes were evaluated based
                      on their signal linearity by calculating a normalized mean
                      FA error between simulated signal intensities and GT B 1 +
                      $$ {\mathrm{B}}_1^{+} $$ data. Additionally, validation
                      measurements of relative B 1 + $$ {\mathrm{B}}_1^{+} $$ maps
                      with the sequential and interleaved acquisition schemes were
                      acquired for the phantom.Validation measurements showed a
                      good agreement with the simulation results for both
                      acquisition schemes and displayed stronger deviations to the
                      GT B 1 + $$ {\mathrm{B}}_1^{+} $$ data for the sequential
                      scheme. The quantitative evaluation yielded higher FA errors
                      for the sequential acquisition scheme for all three regions
                      and all simulated reference voltages. At the same level of
                      error, mean signals were higher for the interleaved
                      acquisition scheme in all cases. Differences between
                      interleaved and sequential acquisition schemes were most
                      pronounced in the steady-state.An interleaved acquisition of
                      channel-wise relative B 1 + $$ {\mathrm{B}}_1^{+} $$ maps
                      extends the range of the linear FA regime, reducing the
                      likelihood of errors and increasing the robustness of the
                      approach.},
      keywords     = {7 Tesla (Other) / B1+ mapping (Other) / heart (Other) /
                      parallel transmission (Other) / prostate (Other) /
                      ultra‐high field (Other)},
      cin          = {E020},
      ddc          = {610},
      cid          = {I:(DE-He78)E020-20160331},
      pnm          = {315 - Bildgebung und Radioonkologie (POF4-315)},
      pid          = {G:(DE-HGF)POF4-315},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:41024603},
      doi          = {10.1002/mrm.70101},
      url          = {https://inrepo02.dkfz.de/record/305028},
}