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@ARTICLE{AlmanzaAguilera:305084,
      author       = {E. Almanza-Aguilera and D. Guananga-Álvarez and Y.
                      Benavente and A. Nieters and C. Besson and F. Saberi
                      Hosnijeh and C. Kyrø and N. P. Bondonno and C. C. Dahm and
                      E. Weiderpass and T. Truong and M. Louati-Hajji and X. Ren
                      and V. Katzke$^*$ and M. B. Schulze and F. Pasanisi and C.
                      Vener and G. Masala and M. T. Giraudo and R. Tumino and A.
                      Aizpurua and M.-J. Sánchez and J. M. Huerta and M. Guevara
                      and C. Lasheras and P. Vineis and R. Vermeulen and R.
                      Zamora-Ros and D. Casabonne},
      title        = {{I}ntake of total, classes, and subclasses of (poly)phenols
                      and risk of lymphoid neoplasms: a prospective analysis in
                      the {EPIC} cohort.},
      journal      = {British journal of cancer},
      volume       = {nn},
      issn         = {0007-0920},
      address      = {Edinburgh},
      publisher    = {Nature Publ. Group},
      reportid     = {DKFZ-2025-02036},
      pages        = {nn},
      year         = {2025},
      note         = {epub},
      abstract     = {Existing epidemiological evidence regarding the potential
                      role of (poly)phenol intake in lymphoma development is
                      limited.We investigated the associations between the intake
                      of total and individual classes and subclasses of
                      (poly)phenols and the risk of lymphoma, including main
                      frequent subtypes in the EPIC cohort using
                      multivariable-adjusted Cox proportional hazards
                      models.During a mean 14-year follow-up (time frame: from
                      1990-1994 to 2008-2013), 2394 incident lymphoma cases were
                      diagnosed from a total of 367,463 individuals. No
                      significant associations were observed between total intakes
                      of (poly)phenols, flavonoids, and phenolic acids and overall
                      lymphoma risk. Total (poly)phenols, phenolic acid and
                      hydroxycinnamic acid intakes were positively associated with
                      Hodgkin lymphoma (HL) risk [HRlog2 = 2.56 $(95\%$ confidence
                      interval: 1.27-5.16); 1.81 (1.14-2.87); and 1.48
                      (1.03-2.12), respectively]. Conversely, isoflavone intakes
                      was inversely associated with risk of overall lymphoma
                      [HRlog2 = 0.96 (0.93-0.99)], and non-Hodgkin lymphoma
                      [HRlog2 = 0.95 (0.92-0.99)] and mature B-cell lymphoma
                      [HRlog2 = 0.96 (0.92-0.99)], and flavone intakes with risk
                      of multiple myeloma/plasma cell neoplasm [HRlog2 = 0.75
                      (0.60-0.95)].Our findings suggest that isoflavone intakes
                      may reduce the risk of overall lymphoma and specific
                      lymphoma subtypes, while phenolic acids, particularly
                      hydroxycinnamic acids might increase the risk of HL.},
      cin          = {C020},
      ddc          = {610},
      cid          = {I:(DE-He78)C020-20160331},
      pnm          = {313 - Krebsrisikofaktoren und Prävention (POF4-313)},
      pid          = {G:(DE-HGF)POF4-313},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:41044175},
      doi          = {10.1038/s41416-025-03228-6},
      url          = {https://inrepo02.dkfz.de/record/305084},
}