TY  - JOUR
AU  - Palmen, Banchia
AU  - Ebadi, Zjala
AU  - van Herck, Maarten
AU  - Goërtz, Yvonne M J
AU  - Deng, Qichen
AU  - Thong, Melissa
AU  - Burtin, Chris
AU  - Peters, Jeannette B
AU  - Sprooten, Roy T M
AU  - Bischoff, Erik W M A
AU  - Wouters, Emiel F M
AU  - Sprangers, Mirjam A G
AU  - Vercoulen, Jan H
AU  - Houben-Wilke, Sarah
AU  - Vaes, Anouk W
AU  - Janssen, Daisy J A
AU  - Spruit, Martijn A
TI  - Bidirectional Associations Between Physical Activity, Sedentary Behavior, and Daily Symptoms in Patients With Chronic Obstructive Pulmonary Disease: Longitudinal Observational Study.
JO  - JMIR mhealth and uhealth
VL  - 13
SN  - 2291-5222
CY  - Toronto
PB  - JMIR Publications
M1  - DKFZ-2025-02194
SP  - e65653 - e65653
PY  - 2025
AB  - Questionnaire-based symptom assessment may introduce recall bias and lacks bidirectional exploration. This is particularly relevant, given the unclear direction of the associations between physical activity (PA), sedentary time (ST), and symptoms in patients with chronic obstructive pulmonary disease (COPD). Understanding these associations could inform symptom management strategies and improve patient quality of life.This study aimed to investigate the direction of the association between PA, ST, and symptoms in patients with COPD using accelerometry and ecological momentary assessment (EMA).A subsample from the FAntasTIGUE study answered 8 randomly timed EMA questionnaires daily for 5 days. Ten symptoms were rated on a 7-point Likert scale: 'I feel relaxed, short of breath, energetic, cheerful, insecure, irritated, satisfied, anxious, tired, and mentally fit.' Concurrently, step count and ST were measured using the ActiGraph GT9X Link placed on the right hip. Step count and ST 15 and 30 minutes pre- and post-EMA were used in multilevel models, controlled for pre-EMA steps and ST, and the previous EMA score. Significant confounders were used as covariates, and patient ID was used as random intercept.Thirty-four patients (19/34, 56
KW  - Humans
KW  - Pulmonary Disease, Chronic Obstructive: psychology
KW  - Pulmonary Disease, Chronic Obstructive: complications
KW  - Male
KW  - Female
KW  - Sedentary Behavior
KW  - Aged
KW  - Longitudinal Studies
KW  - Exercise: psychology
KW  - Exercise: physiology
KW  - Middle Aged
KW  - Surveys and Questionnaires
KW  - Accelerometry: methods
KW  - Accelerometry: instrumentation
KW  - Ecological Momentary Assessment: statistics & numerical data
KW  - Quality of Life: psychology
KW  - COPD (Other)
KW  - accelerometry (Other)
KW  - chronic obstructive pulmonary disease (Other)
KW  - ecological momentary assessment (Other)
KW  - physical activity (Other)
KW  - sedentary behavior (Other)
KW  - symptom assessment (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:41124569
C2  - pmc:PMC12543037
DO  - DOI:10.2196/65653
UR  - https://inrepo02.dkfz.de/record/305510
ER  -