TY - JOUR AU - Peng, Shixuan AU - Chen, Qisheng AU - Liu, Qianzi AU - Xie, Ruijie AU - Wu, Yongjun TI - Association of the American heart association's new 'life's essential 8' cardiovascular health with all-cause and cardiovascular mortality in adults with and without cancer: a retrospective cohort study. JO - BMC cancer VL - 25 IS - 1 SN - 1471-2407 CY - London PB - BioMed Central M1 - DKFZ-2025-02275 SP - 1706 PY - 2025 AB - The American Heart Association released an updated algorithm used to assess cardiovascular health (CVH)-the Life's Essential 8 (LE8) score. Our objective was to quantify the association between CVH levels estimated by the LE8 score and all-cause and cardiovascular mortality in adults with and without cancer.In this retrospective cohort study, 29,352 adults were included from the National Health and Nutrition Examination Survey (NHANES) 2005-2018 at baseline linked to the 2019 National Death Index records. Cox regression models and Restricted cubic spline were used to evaluate the associations between CVH with cardiovascular mortality and all-cause mortality.In this study, 14.8 KW - Humans KW - Cardiovascular Diseases: mortality KW - Neoplasms: mortality KW - Neoplasms: complications KW - Neoplasms: epidemiology KW - Female KW - Male KW - Retrospective Studies KW - Middle Aged KW - Adult KW - American Heart Association KW - Nutrition Surveys KW - United States: epidemiology KW - Aged KW - Cause of Death KW - Cancer (Other) KW - Cardiovascular health (Other) KW - Life's essential 8 (Other) KW - Mortality (Other) LB - PUB:(DE-HGF)16 C6 - pmid:41188772 DO - DOI:10.1186/s12885-025-14464-7 UR - https://inrepo02.dkfz.de/record/305633 ER -