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100 1 _ |a Bekavac, Milica
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245 _ _ |a De novo genome assembly of Ansell's mole-rat (Fukomys anselli).
260 _ _ |a Pittsburgh, PA
|c 2025
|b Genetics Soc. of America
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520 _ _ |a Ansell's mole-rat (Fukomys anselli) is an African rodent known for its subterranean lifestyle and unique phenotypic traits, including extreme longevity, magnetoreception, and a cooperative breeding social structure. Efforts to dissect the genetic architecture of these traits and to decipher their phylogenetic relationships within the broader African mole-rat family would greatly benefit from a reference-grade genome. Here, we report a first genome assembly of a male Ansell's mole-rat. By combining Oxford Nanopore Technologies (ONT) long-reads and Illumina short-reads with Hi-C data, we generated a chromosome level assembly with a total length of 2.27 Gb, 412 scaffolds and a scaffold N50 of 72.4 Mb. We identified 99.54% of expected genes and annotated 29,094 transcripts using RNA sequencing data. This high-quality de novo genome of Fukomys anselli lays the foundation for dissecting the genetic and evolutionary basis of its extraordinary traits and resolving African mole-rat phylogeny.
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650 _ 7 |a Fukomys anselli
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650 _ 7 |a Animalia
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650 _ 7 |a Ansell’s mole-rat
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650 _ 7 |a Bathyergidae
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650 _ 7 |a genome assembly
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650 _ 7 |a mole-rat
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650 _ 7 |a nanopore
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700 1 _ |a Coimbra, Raphael
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700 1 _ |a Busa, Veronica
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700 1 _ |a Behm, Mikaela
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700 1 _ |a Wagner, Rebecca
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700 1 _ |a Goncalves, Angela
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700 1 _ |a Begall, Sabine
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700 1 _ |a Frye, Michaela
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700 1 _ |a Odom, Duncan
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773 _ _ |a 10.1093/g3journal/jkaf271
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