TY  - JOUR
AU  - Kunte, Sophie Carina
AU  - Unterrainer, Lena M
AU  - Lindner, Simon
AU  - Holzgreve, Adrien
AU  - Kunz, Wolfgang G
AU  - Winkelmann, Michael
AU  - Nitschmann, Alexander
AU  - Jurkschat, Klaus
AU  - Wängler, Carmen
AU  - Wängler, Björn
AU  - Schirrmacher, Ralf
AU  - Belka, Claus
AU  - Thon, Niklas
AU  - Schichor, Christian
AU  - Bartenstein, Peter
AU  - Unterrainer, Marcus
TI  - Feasibility of different meningioma delineation approaches on [18F]SiTATE PET/CT imaging.
JO  - Discover oncology
VL  - 16
SN  - 1868-8497
CY  - [New York]
PB  - Springer
M1  - DKFZ-2025-02561
SP  - 2189
PY  - 2025
N1  - Volume 16, article number 2189, (2025) 
AB  - Background:Somatostatin receptor (SSTR)-targeted PET is valuable for meningioma imaging due to high SSTR expression. [18F]SiTATE, a novel tracer, is not only promising for imaging neuroendocrine tumors but also for meningiomas. Standardized delineation methods on [18F]SiTATE PET are lacking. This study correlates CT-based volumes with PET-based delineation approaches to identify a threshold for standardized [18F]SiTATE PET volume assessment.Methods:Patients with well-delineated, extraosseous meningioma on CT (≥ 1mL) who underwent [18F]SiTATE PET/CT were included. Volumes were assessed on contrast-enhanced CT and correlated with PET-based delineation approaches: (I) fixed SUV threshold, (II) isocontour thresholding relative to SUVmax (SUV
KW  - Delineation (Other)
KW  - Isocontour (Other)
KW  - Meningioma (Other)
KW  - SSTR (Other)
KW  - SUV (Other)
KW  - [18F]SiTATE (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:41258525
DO  - DOI:10.1007/s12672-025-04079-6
UR  - https://inrepo02.dkfz.de/record/306345
ER  -