%0 Journal Article
%A Pabst, Kim M
%A Siegmund, Sophie C
%A Holzgreve, Adrien
%A Schmid, Hans P
%A Bartel, Timo
%A Herrmann, Ken
%A Küper, Alina T
%A Aydogdu, Can
%A Kersting, David
%A Kesch, Claudia
%A Hadaschik, Boris A
%A Unterrainer, Marcus
%A Stief, Christian G
%A Cyran, Clemens C
%A Werner, Rudolf A
%A Fendler, Wolfgang P
%A Casuscelli, Jozefina
%A Unterrainer, Lena M
%T Potential value of [68Ga]Ga-FAPI-46 PET in patients with metastatic urothelial carcinoma: a bi-centric analysis.
%J European journal of nuclear medicine and molecular imaging
%V nn
%@ 1619-7070
%C Heidelberg [u.a.]
%I Springer-Verl.
%M DKFZ-2025-02626
%P nn
%D 2025
%Z epub
%X [68Ga]Ga-FAPI-46 has shown promise for urothelial cancer (UC) detection. This study evaluates its diagnostic value versus contrast-enhanced CT (ceCT) and 2-[18F]FDG PET in the largest bi-centric cohort to date.Patients with metastatic UC undergoing [68Ga]Ga-FAPI-46 PET at University Hospitals Munich or Essen were retrospectively reviewed. Detection rates were compared with ceCT on a regional basis (primary, lymph nodes, visceral organs, bone). SUVmax and SUVmean of two index lesions were recorded. In a sub-cohort, [68Ga]Ga-FAPI-46 and 2-[18F]FDG PET were compared on a lesion basis. Clinical follow-up and/or histopathology served as reference.Thirty-four patients underwent [68Ga]Ga-FAPI-46 PET/CT and ceCT, including 10 (29
%K 2-[18F]FDG-PET (Other)
%K CeCT (Other)
%K Detection efficacy (Other)
%K Urothelial carcinoma (Other)
%K [68Ga]Ga-FAPI-46 PET (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:41288692
%R 10.1007/s00259-025-07674-5
%U https://inrepo02.dkfz.de/record/306585