%0 Journal Article
%A Zitricky, Frantisek
%A Sundquist, Kristina
%A Sundquist, Jan
%A Försti, Asta
%A Hemminki, Akseli
%A Hemminki, Kari
%T Second Primary Lung Cancer Associated With Family History of Lung Cancer.
%J Cancer medicine
%V 14
%N 23
%@ 2045-7634
%C Hoboken, NJ
%I Wiley
%M DKFZ-2025-02665
%P e71431
%D 2025
%Z #LA:C020# Z999
%X Familial clustering of initial primary lung cancer (IPLC) may be related to shared smoking habits, other environmental exposures and hereditary factors, but whether familial risk also influences the risk of second primary LC (SPLC) is not well known. We aimed to carry out a family study between first-degree relatives on SPLCs in Sweden.Population data on Swedish family relationships and the diagnosed cancers were obtained from the national registers from 1961 to 2021. IPLC was diagnosed in 54,429 patients of whom 534 were diagnosed with SPLC. Familial risk was assessed through the standardized incidence ratio (SIR with 95
%K Humans
%K Lung Neoplasms: epidemiology
%K Lung Neoplasms: genetics
%K Lung Neoplasms: pathology
%K Female
%K Male
%K Sweden: epidemiology
%K Middle Aged
%K Aged
%K Neoplasms, Second Primary: epidemiology
%K Neoplasms, Second Primary: genetics
%K Registries
%K Risk Factors
%K Incidence
%K Genetic Predisposition to Disease
%K Adult
%K Aged, 80 and over
%K adenocarcinoma (Other)
%K incidence trend (Other)
%K proband (Other)
%K sibling risk (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:41317095
%2 pmc:PMC12664089
%R 10.1002/cam4.71431
%U https://inrepo02.dkfz.de/record/306672