TY  - JOUR
AU  - Laskar, Ruhina S
AU  - Murphy, Neil
AU  - Ferrari, Pietro
AU  - Brennan, Paul
AU  - Cross, Amanda J
AU  - Guevara, Marcela
AU  - Pala, Valeria
AU  - Smith-Byrne, Karl
AU  - Tjønneland, Anne
AU  - Fortner, Renée Turzanski
AU  - Braaten, Tonje Bjørndal
AU  - Nøst, Therese Haugdahl
AU  - Skeie, Guri
AU  - Campbell, Peter T
AU  - Gunter, Marc J
AU  - Borch, Kristin B
TI  - A prospective investigation of early-onset colorectal cancer risk factors-pooled analysis of three large-scale European cohorts.
JO  - British journal of cancer
VL  - nn
SN  - 0007-0920
CY  - Edinburgh
PB  - Nature Publ. Group
M1  - DKFZ-2025-03011
SP  - nn
PY  - 2025
N1  - epub
AB  - Colorectal cancer (CRC) incidence is rising among adults under 55 years, but its causes remain unclear. Large-scale prospective studies are needed to identify risk factors for early-onset CRC (EOCRC).We pooled three large European prospective cohort studies, examining 14 known or suspected risk factors with EOCRC (diagnosed <55 years, N = 1369) and later-onset CRCs (LOCRC) (diagnosed ≥55 years, N = 13,490). Cox proportional hazards models estimated hazard ratios (HRs) and 95
LB  - PUB:(DE-HGF)16
C6  - pmid:41422343
DO  - DOI:10.1038/s41416-025-03303-y
UR  - https://inrepo02.dkfz.de/record/307367
ER  -