TY  - JOUR
AU  - Becht, Selina
AU  - Ben Khaled, Najib
AU  - Schrodi, Simone
AU  - von Bergwelt-Baildon, Michael
AU  - Buggisch, Peter
AU  - Crispin, Alexander
AU  - Hofmann, Wolf-Peter
AU  - Marschall, Ursula
AU  - Mayerle, Julia
AU  - Mörtl, Bernhard
AU  - Orabi, Sami
AU  - Philipp, Alexander
AU  - Trojan, Jörg
AU  - Weiglein, Tobias
AU  - De Toni, Enrico N
AU  - Berger-Thürmel, Karin
TI  - What can claims data tell us about risk factors and survival of patients with hepatocellular carcinoma? Insights from a German population-based study.
JO  - Frontiers in oncology
VL  - 15
SN  - 2234-943X
CY  - Lausanne
PB  - Frontiers Media
M1  - DKFZ-2026-00029
SP  - 1650982
PY  - 2025
AB  - Geographic and temporal variations in the incidence and treatment of chronic viral hepatitis and trends in the development of metabolic and behavioral risk factors result in heterogeneous incidences of hepatocellular carcinoma (HCC). Therefore, national epidemiological information should be evaluated to identify the need for action.This retrospective observational study included adult patients with incident HCC (2016-2020). A network analysis was performed to investigate inter-relationships among risk factor diagnoses before HCC. Kaplan-Meier method and Cox proportional hazard model were used to analyze survival.A total of 2,778 patients were included. Mean age was 71.9 years (SD ±9.7); 69
KW  - cancer epidemiology (Other)
KW  - hepatocellular carcinoma (Other)
KW  - metabolic risk factors (Other)
KW  - real-world evidence (Other)
KW  - secondary data (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:41476582
C2  - pmc:PMC12750458
DO  - DOI:10.3389/fonc.2025.1650982
UR  - https://inrepo02.dkfz.de/record/307524
ER  -