TY  - JOUR
AU  - Walther, Dinah
AU  - Ernst, Jana
AU  - Wollenhaupt, Carola
AU  - Wittig, Susan
AU  - Härtel, Manuela
AU  - Brodt, Grit
AU  - Milde, Till
AU  - Gruhn, Bernd
TI  - Efficacy and Safety of Donor Lymphocyte Infusion After Allogeneic Hematopoietic Stem Cell Transplantation in Pediatric Patients.
JO  - European journal of haematology
VL  - nn
SN  - 0902-4441
CY  - Oxford
PB  - Wiley-Blackwell
M1  - DKFZ-2026-00041
SP  - nn
PY  - 2026
N1  - epub
AB  - This retrospective study evaluates the efficacy and safety of donor lymphocyte infusion (DLI) after allogeneic hematopoietic stem cell transplantation (HSCT) in children. We describe the long-term use of preemptive, prophylactic, and therapeutic DLI with a gradual dose increase in half-log increments. Under close monitoring, we increased the DLI dose only in patients that did not show signs of graft-versus-host disease (GVHD). In the preemptive cohort, 10 of 12 patients (83
KW  - donor chimerism (Other)
KW  - donor lymphocyte infusion (Other)
KW  - graft‐versus‐host disease (Other)
KW  - graft‐versus‐leukemia effect (Other)
KW  - hematopoietic stem cell transplantation (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:41489018
DO  - DOI:10.1111/ejh.70112
UR  - https://inrepo02.dkfz.de/record/307536
ER  -