%0 Journal Article
%A Giehl-Brown, Esther
%A Nikbakhsh, Rajan
%A Bendig, Sarah
%A Radulova-Mauersberger, Olga
%A Schweipert, Johannes
%A Weitz, Jürgen
%A Riediger, Carina
%T Is Extended Lymphadenectomy in Biliary Tract Cancers Justified? A Retrospective Comparative Study of Gallbladder Cancer, Perihilar and Intrahepatic Cholangiocarcinoma.
%J Annals of surgical oncology
%V nn
%@ 1068-9265
%C Berlin [u.a.]
%I Springer
%M DKFZ-2026-00387
%P nn
%D 2026
%Z #NCTZFB9# / epub
%X The oncologic value of lymphadenectomy (LND) in biliary tract cancers (BTC) remains controversial. While guidelines recommend retrieval of ≥ 6 lymph nodes to ensure accurate staging, evidence for a therapeutic survival benefit is limited.We retrospectively analyzed 253 consecutive resections for intrahepatic cholangiocarcinoma (iCCA), perihilar cholangiocarcinoma (pCCA), and gallbladder carcinoma (GBC) at a high‑volume hepatobiliary center from a prospectively maintained database (2013-2023). Patients were stratified into no (0 nodes), limited (1-5 nodes), and extended (≥ 6 nodes) LND. Postoperative morbidity, recurrence-free survival (RFS), and overall survival (OS) were assessed with uni- and multivariable models.LND was performed in 47
%K Biliary tract cancer (Other)
%K Lymphadenectomy (Other)
%K Postoperative morbidity (Other)
%K Recurrence-free survival (Other)
%K Staging accuracy (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:41699355
%R 10.1245/s10434-026-19192-1
%U https://inrepo02.dkfz.de/record/309938