TY  - JOUR
AU  - Giehl-Brown, Esther
AU  - Nikbakhsh, Rajan
AU  - Bendig, Sarah
AU  - Radulova-Mauersberger, Olga
AU  - Schweipert, Johannes
AU  - Weitz, Jürgen
AU  - Riediger, Carina
TI  - Is Extended Lymphadenectomy in Biliary Tract Cancers Justified? A Retrospective Comparative Study of Gallbladder Cancer, Perihilar and Intrahepatic Cholangiocarcinoma.
JO  - Annals of surgical oncology
VL  - nn
SN  - 1068-9265
CY  - Berlin [u.a.]
PB  - Springer
M1  - DKFZ-2026-00387
SP  - nn
PY  - 2026
N1  - #NCTZFB9# / epub
AB  - The oncologic value of lymphadenectomy (LND) in biliary tract cancers (BTC) remains controversial. While guidelines recommend retrieval of ≥ 6 lymph nodes to ensure accurate staging, evidence for a therapeutic survival benefit is limited.We retrospectively analyzed 253 consecutive resections for intrahepatic cholangiocarcinoma (iCCA), perihilar cholangiocarcinoma (pCCA), and gallbladder carcinoma (GBC) at a high‑volume hepatobiliary center from a prospectively maintained database (2013-2023). Patients were stratified into no (0 nodes), limited (1-5 nodes), and extended (≥ 6 nodes) LND. Postoperative morbidity, recurrence-free survival (RFS), and overall survival (OS) were assessed with uni- and multivariable models.LND was performed in 47
KW  - Biliary tract cancer (Other)
KW  - Lymphadenectomy (Other)
KW  - Postoperative morbidity (Other)
KW  - Recurrence-free survival (Other)
KW  - Staging accuracy (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:41699355
DO  - DOI:10.1245/s10434-026-19192-1
UR  - https://inrepo02.dkfz.de/record/309938
ER  -