000309973 001__ 309973 000309973 005__ 20260220120945.0 000309973 0247_ $$2doi$$a10.1007/s11136-025-04129-0 000309973 0247_ $$2pmid$$apmid:41706236 000309973 0247_ $$2ISSN$$a0962-9343 000309973 0247_ $$2ISSN$$a1573-2649 000309973 037__ $$aDKFZ-2026-00399 000309973 041__ $$aEnglish 000309973 082__ $$a100 000309973 1001_ $$00000-0003-1690-631X$$aLizano-Barrantes, Catalina$$b0 000309973 245__ $$aNeeds and health-related quality of life domains relevant to people in Europe with advanced cancer in need of palliative care: a systematic review of qualitative research. 000309973 260__ $$aCham$$bSpringer Nature Switzerland AG$$c2026 000309973 3367_ $$2DRIVER$$aarticle 000309973 3367_ $$2DataCite$$aOutput Types/Journal article 000309973 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1771576728_3240617$$xReview Article 000309973 3367_ $$2BibTeX$$aARTICLE 000309973 3367_ $$2ORCID$$aJOURNAL_ARTICLE 000309973 3367_ $$00$$2EndNote$$aJournal Article 000309973 520__ $$aThere is a need for a comprehensive summary of qualitative research on the health-related quality of life (HRQoL) of people with advanced cancer requiring palliative care. We aim to systematically review qualitative studies on outcomes, needs, experiences, preferences, concerns and HRQoL of people in Europe with advanced cancer requiring palliative care over the last decade.Protocol registered ( www.crd.york.ac.uk/PROSPERO , CRD42024575065). The search was conducted in PubMed and Scopus, from 2013 onward.qualitative studies addressing constructs related to the HRQoL of adults with cancer requiring palliative care in Europe. Abstracts and full texts were reviewed, data extracted, and risk of bias assessed independently by two researchers. A thematic analysis stratified by study objective was performed, grouping the emerging themes into categories (primary outcome).Of 18,256 articles identified, 20 fulfilled the inclusion criteria: 10 studies with a generic objective (whole palliative process or end-of-life phase), and 10 with specific focuses. Five categories (35 themes) emerged from the studies with generic focuses: 'Psychological Function' (n = 15), 'Clinical Management' (n = 8), 'Symptoms and Physical Function' (n = 6), 'Social Function' (n = 5), and 'End-of-life' (n = 1). Themes from the 7 studies focusing on treatment, services, and self-management also fitted into these categories, adding 'Spiritual Well-being'.These findings emphasise the predominance of the psychological function domain in cancer patients requiring palliative care, including cancer-related anxiety and distress, coping mechanisms, control and decision-making, and fearing and expecting death. Additionally, clinical management unmet needs were identified in health care, information and communication, and end-of-life settings (home vs. hospital). 000309973 536__ $$0G:(DE-HGF)POF4-313$$a313 - Krebsrisikofaktoren und Prävention (POF4-313)$$cPOF4-313$$fPOF IV$$x0 000309973 588__ $$aDataset connected to CrossRef, PubMed, , Journals: inrepo02.dkfz.de 000309973 650_7 $$2Other$$aCancer 000309973 650_7 $$2Other$$aNeoplasms 000309973 650_7 $$2Other$$aPalliative care 000309973 650_7 $$2Other$$aQualitative research 000309973 650_7 $$2Other$$aQuality of life 000309973 650_7 $$2Other$$aSystematic review 000309973 650_2 $$2MeSH$$aHumans 000309973 650_2 $$2MeSH$$aPalliative Care: psychology 000309973 650_2 $$2MeSH$$aQuality of Life: psychology 000309973 650_2 $$2MeSH$$aQualitative Research 000309973 650_2 $$2MeSH$$aNeoplasms: psychology 000309973 650_2 $$2MeSH$$aNeoplasms: therapy 000309973 650_2 $$2MeSH$$aEurope 000309973 7001_ $$00000-0001-9595-0970$$aAmat-Fernandez, Clara$$b1 000309973 7001_ $$00000-0001-6193-0779$$aGarin, Olatz$$b2 000309973 7001_ $$00009-0004-7730-0658$$aLuer-Aguila, Ricardo$$b3 000309973 7001_ $$00000-0003-4982-5495$$aPardo, Yolanda$$b4 000309973 7001_ $$00000-0002-6814-7426$$aRojas-Concha, Leslye$$b5 000309973 7001_ $$0P:(DE-He78)24fe6057396bec79d2638615b12eb989$$aThong, Melissa$$b6$$udkfz 000309973 7001_ $$00000-0001-5179-104X$$aApolone, Giovanni$$b7 000309973 7001_ $$00000-0003-3905-1289$$aBrunelli, Cinzia$$b8 000309973 7001_ $$00000-0002-0375-6204$$aCaraceni, Augusto$$b9 000309973 7001_ $$aCouespel, Norbert$$b10 000309973 7001_ $$aBos, Nanne$$b11 000309973 7001_ $$aGroenvold, Mogens$$b12 000309973 7001_ $$aKaasa, Stein$$b13 000309973 7001_ $$00000-0003-2851-8605$$aCiliberto, Gennaro$$b14 000309973 7001_ $$00000-0001-7554-449X$$aLombardo, Claudio$$b15 000309973 7001_ $$aPietrobon, Ricardo$$b16 000309973 7001_ $$00000-0002-4843-4663$$aPravettoni, Gabriella$$b17 000309973 7001_ $$00009-0007-8222-0961$$aSirven, Aude$$b18 000309973 7001_ $$00000-0003-1259-649X$$aVachon, Hugo$$b19 000309973 7001_ $$00000-0002-9142-1227$$aGilbert, Alexandra$$b20 000309973 7001_ $$00000-0003-1899-5942$$aVelikova, Galina$$b21 000309973 7001_ $$00000-0001-9867-7391$$aFerrer, Montse$$b22 000309973 7001_ $$aGroup, EUonQoL Working$$b23$$eCollaboration Author 000309973 7001_ $$aCiuleanu, Tudor$$b24$$eContributor 000309973 7001_ $$aMitrić, Milana$$b25$$eContributor 000309973 7001_ $$aRatosa, Ivica$$b26$$eContributor 000309973 7001_ $$aChovanec, Michal$$b27$$eContributor 000309973 7001_ $$aVieito, Maria$$b28$$eContributor 000309973 7001_ $$aAguilar, Héctor$$b29$$eContributor 000309973 7001_ $$aRuiz, Eva$$b30$$eContributor 000309973 7001_ $$aAhlberg, Karin$$b31$$eContributor 000309973 7001_ $$aSimsek, Eda Tanrikulu$$b32$$eContributor 000309973 7001_ $$aGumus, Mahmut$$b33$$eContributor 000309973 7001_ $$avan Braak, Inke$$b34$$eContributor 000309973 7001_ $$aHiggins, Caitriona$$b35$$eContributor 000309973 7001_ $$aPinnavaia, Laura$$b36$$eContributor 000309973 7001_ $$aDantas, Carina$$b37$$eContributor 000309973 7001_ $$aKalmi, Tapani$$b38$$eContributor 000309973 773__ $$0PERI:(DE-600)2008960-0$$a10.1007/s11136-025-04129-0$$gVol. 35, no. 3, p. 74$$n3$$p74$$tQuality of life research$$v35$$x0962-9343$$y2026 000309973 909CO $$ooai:inrepo02.dkfz.de:309973$$pVDB 000309973 9101_ $$0I:(DE-588b)2036810-0$$6P:(DE-He78)24fe6057396bec79d2638615b12eb989$$aDeutsches Krebsforschungszentrum$$b6$$kDKFZ 000309973 9131_ $$0G:(DE-HGF)POF4-313$$1G:(DE-HGF)POF4-310$$2G:(DE-HGF)POF4-300$$3G:(DE-HGF)POF4$$4G:(DE-HGF)POF$$aDE-HGF$$bGesundheit$$lKrebsforschung$$vKrebsrisikofaktoren und Prävention$$x0 000309973 9141_ $$y2026 000309973 915__ $$0StatID:(DE-HGF)0430$$2StatID$$aNational-Konsortium$$d2024-12-18$$wger 000309973 915__ $$0StatID:(DE-HGF)3002$$2StatID$$aDEAL Springer$$d2024-12-18$$wger 000309973 915__ $$0StatID:(DE-HGF)3002$$2StatID$$aDEAL Springer$$d2024-12-18$$wger 000309973 915__ $$0StatID:(DE-HGF)0100$$2StatID$$aJCR$$bQUAL LIFE RES : 2022$$d2024-12-18 000309973 915__ $$0StatID:(DE-HGF)0200$$2StatID$$aDBCoverage$$bSCOPUS$$d2024-12-18 000309973 915__ $$0StatID:(DE-HGF)0300$$2StatID$$aDBCoverage$$bMedline$$d2024-12-18 000309973 915__ $$0StatID:(DE-HGF)0600$$2StatID$$aDBCoverage$$bEbsco Academic Search$$d2024-12-18 000309973 915__ $$0StatID:(DE-HGF)0030$$2StatID$$aPeer Review$$bASC$$d2024-12-18 000309973 915__ $$0StatID:(DE-HGF)0199$$2StatID$$aDBCoverage$$bClarivate Analytics Master Journal List$$d2024-12-18 000309973 915__ $$0StatID:(DE-HGF)0160$$2StatID$$aDBCoverage$$bEssential Science Indicators$$d2024-12-18 000309973 915__ $$0StatID:(DE-HGF)1180$$2StatID$$aDBCoverage$$bCurrent Contents - Social and Behavioral Sciences$$d2024-12-18 000309973 915__ $$0StatID:(DE-HGF)0130$$2StatID$$aDBCoverage$$bSocial Sciences Citation Index$$d2024-12-18 000309973 915__ $$0StatID:(DE-HGF)1110$$2StatID$$aDBCoverage$$bCurrent Contents - Clinical Medicine$$d2024-12-18 000309973 915__ $$0StatID:(DE-HGF)0113$$2StatID$$aWoS$$bScience Citation Index Expanded$$d2024-12-18 000309973 915__ $$0StatID:(DE-HGF)0150$$2StatID$$aDBCoverage$$bWeb of Science Core Collection$$d2024-12-18 000309973 915__ $$0StatID:(DE-HGF)9900$$2StatID$$aIF < 5$$d2024-12-18 000309973 9201_ $$0I:(DE-He78)C071-20160331$$kC071$$lCancer Survivorship$$x0 000309973 980__ $$ajournal 000309973 980__ $$aVDB 000309973 980__ $$aI:(DE-He78)C071-20160331 000309973 980__ $$aUNRESTRICTED