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| Home > Publications database > Are levels of DHEAS indicative of subjective health - results of the population-based longitudinal CARLA study. > print |
| Home > Publications database > Are levels of DHEAS indicative of subjective health - results of the population-based longitudinal CARLA study. > print |
| 001 | 309979 | ||
| 005 | 20260220160047.0 | ||
| 024 | 7 | _ | |a 10.1038/s41514-026-00346-0 |2 doi |
| 024 | 7 | _ | |a pmid:41714619 |2 pmid |
| 024 | 7 | _ | |a 2056-3973 |2 ISSN |
| 024 | 7 | _ | |a 2731-6068 |2 ISSN |
| 037 | _ | _ | |a DKFZ-2026-00405 |
| 041 | _ | _ | |a English |
| 100 | 1 | _ | |a Behr, Luise Charlotte |b 0 |
| 245 | _ | _ | |a Are levels of DHEAS indicative of subjective health - results of the population-based longitudinal CARLA study. |
| 260 | _ | _ | |a [London] |c 2026 |b Springer Nature |
| 336 | 7 | _ | |a article |2 DRIVER |
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| 336 | 7 | _ | |a Journal Article |b journal |m journal |0 PUB:(DE-HGF)16 |s 1771599632_3240619 |2 PUB:(DE-HGF) |
| 336 | 7 | _ | |a ARTICLE |2 BibTeX |
| 336 | 7 | _ | |a JOURNAL_ARTICLE |2 ORCID |
| 336 | 7 | _ | |a Journal Article |0 0 |2 EndNote |
| 500 | _ | _ | |a epub |
| 520 | _ | _ | |a Subjective and objective markers are important in describing healthy aging, yet little is known about their relationships. This study analysed the time-dependent association of dehydroepiandrosterone sulfate (DHEAS) with subjective health. At baseline, DHEAS was measured in participants aged 45-83 randomly selected from the general population. Subjective mental and physical health were assessed using the 12-item Short Form (SF-12) questionnaire at baseline and two follow-ups. In sex-specific linear regression models controlled for age, weight, tobacco consumption, Charlson Comorbidity Index, depression, and testosterone levels, the associations of DHEAS with the subscores of the SF-12 were analysed. DHEAS showed a positive cross-sectional association with subjective physical health, which was stronger in women and remained relevant after multivariable adjustment. However, longitudinal analyses revealed no long-term effect of DHEAS on subjective health. These findings suggest that the association between DHEAS and subjective physical health is temporary and that an underlying causality is unlikely. |
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| 700 | 1 | _ | |a Kluttig, Alexander |b 1 |
| 700 | 1 | _ | |a Simm, Andreas |b 2 |
| 700 | 1 | _ | |a Mikolajczyk, Rafael |b 3 |
| 700 | 1 | _ | |a Kraus, Frank Bernhard |b 4 |
| 700 | 1 | _ | |a Sedding, Daniel |b 5 |
| 700 | 1 | _ | |a Greiser, Karin Halina |0 P:(DE-He78)e0ac0d57cdb66d87f2d95ae5f6178c1b |b 6 |u dkfz |
| 700 | 1 | _ | |a Wienke, Andreas |b 7 |
| 700 | 1 | _ | |a Großkopf, Anne |b 8 |
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