TY - JOUR
AU - Lanzafame, Helena
AU - Mavroeidi, Ilektra A
AU - Pabst, Kim M
AU - Fragoso Costa, Pedro
AU - Schuler, Martin
AU - Bauer, Sebastian
AU - Kurth, Jens
AU - Heuschkel, Martin
AU - Siveke, Jens T
AU - Herrmann, Ken
AU - Kostbade, Karina
AU - Kersting, David
AU - Leyser, Stephan
AU - Fröhling, Stefan
AU - Heilig, Christoph E
AU - Hamacher, Rainer
AU - Fendler, Wolfgang P
TI - 90Y-FAPI-46 Radiopharmaceutical Therapy in Sarcoma and Other Solid Tumors: An Updated Cohort Analysis.
JO - Journal of nuclear medicine
VL - nn
SN - 0097-9058
CY - New York, NY
PB - Soc.
M1 - DKFZ-2026-00406
SP - nn
PY - 2026
N1 - epub
AB - Fibroblast activation protein (FAP) is highly expressed in many cancers, especially sarcomas, and represents a promising theranostic target. We present an updated retrospective analysis of 90Y-FAP inhibitor (FAPI)-46 treatment in patients with sarcoma or other solid tumors. Methods: We performed monocentric analysis of patients with progressive sarcoma or metastatic cancer who were eligible for 90Y-FAPI-46 therapy after approved treatments had been exhausted and who showed high FAP expression (SUVmax, ≥10 in over 50
KW - 90Y-FAPI-46 (Other)
KW - radiopharmaceutical therapy (Other)
KW - sarcomas (Other)
KW - theranostics (Other)
LB - PUB:(DE-HGF)16
C6 - pmid:41714122
DO - DOI:10.2967/jnumed.125.271135
UR - https://inrepo02.dkfz.de/record/309980
ER -