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@ARTICLE{Warz:310335,
author = {S.-I. Warz$^*$ and K. Lundervold and V. Katzke$^*$ and R.
K. Lein and C. Tzoulis and J. Dierkes},
title = {{D}airy and {M}ilk {I}ntake and {R}isk for {P}arkinson's
{D}isease in {W}omen and {M}en: {A} {S}ystematic {R}eview
and {M}eta-{A}nalysis.},
journal = {Movement disorders clinical practice},
volume = {nn},
issn = {2330-1619},
address = {New York, NY},
publisher = {Wiley},
reportid = {DKFZ-2026-00536},
pages = {nn},
year = {2026},
note = {#EA:C020# / epub},
abstract = {Parkinson's disease is the second most common
neurodegenerative disorder, with environmental factors
influencing the risk. The role of dairy consumption is
controversial, despite repeated with Parkinson's disease in
epidemiological studies.We conducted a systematic review and
meta-analysis to evaluate sex-specific associations between
dairy intake and Parkinson's disease risk.A literature
search was performed using the Medline and EMBASE databases.
Out of 649 studies, eight cohort studies were included in
the systematic review, covering 578,736 participants and
4816 Parkinson's disease cases from seven countries. For the
meta-analyses, a Restricted Maximum Likelihood random effect
model was used to derive the pooled estimates stratified by
sex for six prospective cohort studies comparing the highest
versus the lowest intake quantile. Results revealed a
sex-specific effect of dairy intake, a significant
association with a higher risk of Parkinson's disease in
males (HR 1.28, 1.05-1.56), whereas no association was
observed in females (HR 1.02, 0.80-1.30). For milk intake
only, estimates were 1.36 (0.97-1.90) for males and 1.19
(0.94-1.51) for females.Our meta-analysis found an
association between dairy consumption and Parkinson's
disease risk in males, but not in females. There was also an
almost significant association between milk intake and risk
of Parkinson's disease, which was stronger in males than in
females. However, the evidence for this association remains
weak. Further studies with larger sex-stratified samples
across diverse countries are needed to clarify sex
differences and establish significant associations.},
subtyp = {Review Article},
cin = {C020},
ddc = {610},
cid = {I:(DE-He78)C020-20160331},
pnm = {313 - Krebsrisikofaktoren und Prävention (POF4-313)},
pid = {G:(DE-HGF)POF4-313},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:41792943},
doi = {10.1002/mdc3.70575},
url = {https://inrepo02.dkfz.de/record/310335},
}