2023-01-30 10:39 |
[DKFZ-2023-00218]
Journal Article
Patel Jamilkhan, A. ; Khan, F. A. ; Sikdar, A. ; et al
Test for Non-Synergistic Interactions in Phytomedicine, Just as You Do for Isolated Compounds
Phytomedicine has often been used as “alternative therapy,” which in our opinion is unfortunate as it prevents its main actionsbeing systematically studied, side effects explored, and toxicity tested, like all single-compound-based medicine. Our group is interested infinding which traditional or modern phytomedicines actually work and which are simply “working” through placebo, standardizing phytomedicinepreparations, studying their toxicity, and finding active molecules in plants for modification and chemical synthesis as single compounds.Although fluctuation in efficacy due to seasonal and geographical variations in phytomedicine remains a concern, if well regulated, even plantextracts without isolated compounds can serve medicinal needs where single-compound options are currently not great. [...]
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2023-01-30 10:29 |
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2023-01-30 10:28 |
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2023-01-30 10:27 |
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2023-01-30 10:26 |
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2023-01-30 10:24 |
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2023-01-30 10:23 |
[DKFZ-2023-00211]
Journal Article
Chen, Y. ; Jin, D. ; Guo, B. ; et al
Attention-Assisted Adversarial Model for Cerebrovascular Segmentation in 3D TOF-MRA Volumes
Cerebrovascular segmentation in time-offlight magnetic resonance angiography (TOF-MRA) volumesis essential for a variety of diagnostic and analytical applications. However, accurate cerebrovascular segmentationin 3D TOF-MRA is faced with multiple issues, including vastvariations in cerebrovascular morphology and intensity,noisy background, and severe class imbalance betweenforeground cerebral vessels and background.In this work, a3D adversarial network model called A-SegAN is proposedto segment cerebral vessels in TOF-MRA volumes. [...]
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2023-01-30 10:21 |
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2023-01-30 10:19 |
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2023-01-30 10:18 |
[DKFZ-2023-00208]
Journal Article
Niu, Y. ; Teng, X. ; Zhou, H. ; et al
Characterizing mobile element insertions in 5675 genomes
Mobile element insertions (MEIs) are a major class of structural variants (SVs) and have been linked to many human genetic disorders, including hemophilia, neurofibromatosis, and various cancers. However, human MEI resources from large-scale genome sequencing are still lacking compared to those for SNPs and SVs. [...]
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