Open Access

This fact sheet aims to inform about the main epidemiological statistics and trends as well as the economic burden of prostate cancer (ICD-10-GM C61) in Germany. For the epidemiology figures, data from the German Centre for Cancer Registry Data (ZfKD) at Robert Koch Institute (RKI) was used. [...]

This fact sheet provides epidemiology statistics as well as information on the economic burden of lung cancer in Germany. Epidemiology figures have been constructed from records of the German Centre for Cancer Registry Data (ZfKD) at the Robert Koch Institute. [...]

This fact sheet provides epidemiology statistics as well as economic burden of disease information on colorectal cancer (CRC) in Germany. Epidemiology figures are constructed from the records of the German Centre for Cancer Registry Data (ZfKD) at the Robert Koch Institute (RKI). [...]

L-Tryptophan (Trp) metabolism through the kynurenine pathway (KP) is involved in the regulation of immunity, neuronal function and intestinal homeostasis. Imbalances in Trp metabolism in disorders ranging from cancer to neurodegenerative disease have stimulated interest in therapeutically targeting the KP, particularly the main rate-limiting enzymes indoleamine-2,3-dioxygenase 1 (IDO1), IDO2 and tryptophan-2,3-dioxygenase (TDO) as well as kynurenine monooxygenase (KMO). [...]