F190
NWG Cell Plasticity and Epigenetic Remodeling
Also known as: F190 Cell Plasticity and Epigenetic Remodeling; F190 NWG Cell Plasticity and Epigenetic Remodeling
ID I:(DE-He78)F190-20160331
Recent Publications All known publications ... Download: BibTeX | EndNote XML , Text | RIS |
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Breinig, M. ; Lomakin, A. (First author) DKFZ * ; Heidari, E. (First author) DKFZ * ; Ritter, M. DKFZ * ; Rukhovich, G. DKFZ * ; Böse, L. ; Butthof, L. ; Wendler-Link, L. ; Wiethoff, H. ; Poth, T. ; Sahm, F. DKFZ * ; Schirmacher, P. ; Stegle, O. DKFZ * ; Gerstung, M. DKFZ * ; Tschaharganeh, D. F. (Last author) DKFZ *
Integrated in vivo combinatorial functional genomics and spatial transcriptomics of tumours to decode genotype-to-phenotype relationships.
Nature biomedical engineering nn , nn (2025 ) [10.1038/s41551-025-01437-1 ] 2025
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Lim, B. (First author) DKFZ * ; Kamal, A. ; Gomez Ramos, B. DKFZ * ; Adrian Segarra, J. DKFZ * ; Ibarra, I. L. ; Dignas, L. DKFZ * ; Kindinger, T. DKFZ * ; Volz, K. DKFZ * ; Rahbari, M. DKFZ * ; Rahbari, N. ; Poisel, E. DKFZ * ; Kafetzopoulou, K. DKFZ * ; Böse, L. DKFZ * ; Breinig, M. DKFZ * ; Heide, D. DKFZ * ; Gallage, S. U. DKFZ * ; Barragan Avila, J. E. DKFZ * ; Wiethoff, H. ; Berest, I. ; Schnabellehner, S. ; Schneider, M. DKFZ * ; Becker, J. DKFZ * ; Helm, D. DKFZ * ; Grimm, D. ; Mäkinen, T. ; Tschaharganeh, D. F. DKFZ * ; Heikenwalder, M. DKFZ * ; Zaugg, J. B. ; Mall, M. (Last author) DKFZ *
Active repression of cell fate plasticity by PROX1 safeguards hepatocyte identity and prevents liver tumorigenesis.
Nature genetics 57 (3 ), 668-679 (2025 ) [10.1038/s41588-025-02081-w ] 2025
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Jiang, X. (First author) DKFZ * ; Baig, A. H. (First author) DKFZ * ; Palazzo, G. DKFZ * ; Del Pizzo, R. DKFZ * ; Bortecen, T. DKFZ * ; Groessl, S. DKFZ * ; Zaal, E. A. ; Amaya Ramirez, C. C. DKFZ * ; Kowar, A. DKFZ * ; Aviles-Huerta, D. DKFZ * ; Berkers, C. R. ; Palm, W. DKFZ * ; Tschaharganeh, D. DKFZ * ; Krijgsveld, J. (Last author) DKFZ * ; Loayza-Puch, F. (Last author) DKFZ *
P53-dependent hypusination of eIF5A affects mitochondrial translation and senescence immune surveillance.
Nature Communications 15 (1 ), 7458 (2024 ) [10.1038/s41467-024-51901-w ] 2024
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Krieg, S. (First author) DKFZ * ; Rohde, T. ; Rausch, T. ; Butthof, L. DKFZ * ; Wendler-Link, L. DKFZ * ; Eckert, C. DKFZ * ; Breuhahn, K. ; Galy, B. DKFZ * ; Korbel, J. ; Billmann, M. ; Breinig, M. DKFZ * ; Tschaharganeh, D. F. (Last author) DKFZ *
Mitoferrin2 is a synthetic lethal target for chromosome 8p deleted cancers.
Genome medicine 16 (1 ), 83 (2024 ) [10.1186/s13073-024-01357-w ] 2024
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Hasche, D. (First author) DKFZ * ; Hufbauer, M. ; Braspenning-Wesch, I. DKFZ * ; Stephan, S. DKFZ * ; Silling, S. ; Schmidt, G. DKFZ * ; Krieg, S. DKFZ * ; Kreuter, A. ; Akgül, B.
Cytokeratin-17 expression is commonly observed in keratinocytic skin tumours and controls tissue homeostasis impacting HPV protein expression.
British journal of dermatology 191 (6 ), 949-963 (2024 ) [10.1093/bjd/ljae255 ] 2024
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Tran, C. S. ; Kersten, J. ; Yan, J. ; Breinig, M. DKFZ * ; Huth, T. ; Poth, T. ; Colasanti, O. ; Riedl, T. DKFZ * ; Faure-Dupuy, S. ; Diehl, S. ; Verhoye, L. ; Li, T.-F. ; Lingemann, M. ; Schult, P. ; Ahlén, G. ; Frelin, L. ; Kühnel, F. ; Vondran, F. W. R. ; Breuhahn, K. ; Meuleman, P. ; Heikenwälder, M. ; Schirmacher, P. ; Bartenschlager, R. DKFZ * ; Laketa, V. ; Roessler, S. ; Tschaharganeh, D. F. DKFZ * ; Sällberg, M. ; Lohmann, V.
Phosphatidylinositol 4-kinase III alpha governs cytoskeletal organization for invasiveness of liver cancer cells.
Gastroenterology 167 (3 ), 522-537 (2024 ) [10.1053/j.gastro.2024.04.009 ] 2024
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Scherr, A.-L. ; Nader, L. ; Xu, K. ; Elssner, C. ; Ridder, D. A. ; Nichetti, F. ; Mastel, M. DKFZ * ; Fritzsche, S. ; Kelmendi, E. ; Schmitt, N. ; Hoffmeister-Wittmann, P. ; Weiler, S. M. E. ; Korell, F. DKFZ * ; Albrecht, T. ; Schwab, M. ; Isele, H. ; Kessler, A. ; Hüllein, J. ; Seretny, A. DKFZ * ; Ye, L. ; Urbanik, T. ; Welte, S. ; Leblond, A.-L. ; Heilig, C. DKFZ * ; Rahbari, M. DKFZ * ; Ali, A. DKFZ * ; Gallage, S. U. DKFZ * ; Lenoir, B. M. A. DKFZ * ; Wilhelm, N. DKFZ * ; Gärtner, U. ; Ogrodnik, S. J. DKFZ * ; Springfeld, C. ; Tschaharganeh, D. F. DKFZ * ; Fröhling, S. DKFZ * ; Longerich, T. ; Schulze-Bergkamen, H. ; Jäger, D. DKFZ * ; Brandl, L. ; Schirmacher, P. ; Straub, B. K. ; Weber, A. ; De Toni, E. N. ; Goeppert, B. ; Heikenwälder, M. DKFZ * ; Jackstadt, R.-F. DKFZ * ; Roessler, S. ; Breuhahn, K. ; Köhler, B. C. DKFZ *
Etiology-independent activation of the LTβ-LTβR-RELB axis drives aggressiveness and predicts poor prognosis in Hepatocellular carcinoma.
Hepatology 80 (2 ), 278-294 (2024 ) [10.1097/HEP.0000000000000657 ] 2024
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Zhu, C. ; Soto-Feliciano, Y. M. ; Morris, J. P. ; Huang, C.-H. ; Koche, R. P. ; Ho, Y.-J. ; Banito, A. ; Chen, C.-W. ; Shroff, A. ; Tian, S. ; Livshits, G. ; Chen, C.-C. ; Fennell, M. ; Armstrong, S. A. ; Allis, C. D. ; Tschaharganeh, D. F. DKFZ * ; Lowe, S. W.
MLL3 regulates the CDKN2A tumor suppressor locus in liver cancer.
eLife 12 , e80854 (2023 ) [10.7554/eLife.80854 ] 2023
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Schifflers, C. (First author) DKFZ * ; Zottnick, S. DKFZ * ; Förster, J. DKFZ * ; Kruse, S. DKFZ * ; Yang, R. DKFZ * ; Wiethoff, H. DKFZ * ; Bozza, M. DKFZ * ; Hoppe-Seyler, K. DKFZ * ; Heikenwälder, M. DKFZ * ; Harbottle, R. P. DKFZ * ; Michiels, C. ; Riemer, A. (Last author) DKFZ *
Development of an Orthotopic HPV16-Dependent Base of Tongue Tumor Model in MHC-Humanized Mice.
Pathogens 12 (2 ), 188 (2023 ) [10.3390/pathogens12020188 ] 2023
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Sorrentino, A. (First author) DKFZ * ; Menevse, A. N. ; Michels, T. DKFZ * ; Volpin, V. DKFZ * ; Durst, F. C. ; Sax, J. ; Xydia, M. ; Hussein, A. ; Stamova, S. ; Spoerl, S. ; Heuschneider, N. ; Muehlbauer, J. ; Jeltsch, K. M. ; Rathinasamy, A. ; Werner-Klein, M. ; Breinig, M. DKFZ * ; Mikietyn, D. ; Kohler, C. ; Poschke, I. DKFZ * ; Purr, S. DKFZ * ; Reidell, O. ; Martins Freire, C. ; Offringa, R. DKFZ * ; Gebhard, C. ; Spang, R. ; Rehli, M. ; Boutros, M. DKFZ * ; Schmidl, C. ; Khandelwal, N. DKFZ * ; Beckhove, P. (Last author) DKFZ *
Salt-inducible kinase 3 protects tumor cells from cytotoxic T-cell attack by promoting TNF-induced NF-κB activation.
Journal for ImmunoTherapy of Cancer 10 (5 ), e004258 (2022 ) [10.1136/jitc-2021-004258 ] 2022
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All known publications ... Download: BibTeX | EndNote XML , Text | RIS |