%0 Journal Article
%A Bozzai, Barbara
%A Hasselblatt, Martin
%A Turányi, Eszter
%A Frühwald, Michael C
%A Siebert, Reiner
%A Bens, Susanne
%A Schneppenheim, Reinhard
%A Kool, Marcel
%A Stelczer, Gábor
%A Hortobágyi, Tibor
%A Hauser, Peter
%T Atypical teratoid/rhabdoid tumor arising in a malignant glioma.2
%J Pediatric blood & cancer
%V 64
%N 1
%@ 1545-5009
%C New York, NY
%I Wiley
%M DKFZ-2017-00013
%P 96 - 99
%D 2017
%X Atypical teratoid/rhabdoid tumor (AT/RT), a highly malignant brain tumor in young children, usually arises de novo and has only rarely been described as a secondary malignancy. Here, we present a case of a child with glioblastoma, who was treated postoperatively by a combination of temozolomide, irradiation, and bevacizumab. AT/RT was diagnosed as a secondary tumor, 2.5 years following primary diagnosis. The child died 13 months after the diagnosis of AT/RT. This case demonstrates that malignant gliomas may give rise to AT/RT. It also emphasizes the diagnostic value of a repeated tumor biopsy in the recurrence setting.
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:27472468
%R 10.1002/pbc.26173
%U https://inrepo02.dkfz.de/record/119223