TY  - JOUR
AU  - Bozzai, Barbara
AU  - Hasselblatt, Martin
AU  - Turányi, Eszter
AU  - Frühwald, Michael C
AU  - Siebert, Reiner
AU  - Bens, Susanne
AU  - Schneppenheim, Reinhard
AU  - Kool, Marcel
AU  - Stelczer, Gábor
AU  - Hortobágyi, Tibor
AU  - Hauser, Peter
TI  - Atypical teratoid/rhabdoid tumor arising in a malignant glioma.2
JO  - Pediatric blood & cancer
VL  - 64
IS  - 1
SN  - 1545-5009
CY  - New York, NY
PB  - Wiley
M1  - DKFZ-2017-00013
SP  - 96 - 99
PY  - 2017
AB  - Atypical teratoid/rhabdoid tumor (AT/RT), a highly malignant brain tumor in young children, usually arises de novo and has only rarely been described as a secondary malignancy. Here, we present a case of a child with glioblastoma, who was treated postoperatively by a combination of temozolomide, irradiation, and bevacizumab. AT/RT was diagnosed as a secondary tumor, 2.5 years following primary diagnosis. The child died 13 months after the diagnosis of AT/RT. This case demonstrates that malignant gliomas may give rise to AT/RT. It also emphasizes the diagnostic value of a repeated tumor biopsy in the recurrence setting.
LB  - PUB:(DE-HGF)16
C6  - pmid:27472468
DO  - DOI:10.1002/pbc.26173
UR  - https://inrepo02.dkfz.de/record/119223
ER  -