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001     119223
005     20240228145428.0
024 7 _ |a 10.1002/pbc.26173
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024 7 _ |a pmid:27472468
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024 7 _ |a 0098-1532
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024 7 _ |a 1096-911X
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024 7 _ |a 1545-5009
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024 7 _ |a 1545-5017
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037 _ _ |a DKFZ-2017-00013
041 _ _ |a eng
082 _ _ |a 610
100 1 _ |a Bozzai, Barbara
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245 _ _ |a Atypical teratoid/rhabdoid tumor arising in a malignant glioma.2
260 _ _ |a New York, NY
|c 2017
|b Wiley
336 7 _ |a article
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336 7 _ |a ARTICLE
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336 7 _ |a Journal Article
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520 _ _ |a Atypical teratoid/rhabdoid tumor (AT/RT), a highly malignant brain tumor in young children, usually arises de novo and has only rarely been described as a secondary malignancy. Here, we present a case of a child with glioblastoma, who was treated postoperatively by a combination of temozolomide, irradiation, and bevacizumab. AT/RT was diagnosed as a secondary tumor, 2.5 years following primary diagnosis. The child died 13 months after the diagnosis of AT/RT. This case demonstrates that malignant gliomas may give rise to AT/RT. It also emphasizes the diagnostic value of a repeated tumor biopsy in the recurrence setting.
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700 1 _ |a Hasselblatt, Martin
|b 1
700 1 _ |a Turányi, Eszter
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700 1 _ |a Frühwald, Michael C
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700 1 _ |a Siebert, Reiner
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700 1 _ |a Bens, Susanne
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700 1 _ |a Schneppenheim, Reinhard
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700 1 _ |a Kool, Marcel
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700 1 _ |a Stelczer, Gábor
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700 1 _ |a Hortobágyi, Tibor
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700 1 _ |a Hauser, Peter
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773 _ _ |a 10.1002/pbc.26173
|g Vol. 64, no. 1, p. 96 - 99
|0 PERI:(DE-600)2130978-4
|n 1
|p 96 - 99
|t Pediatric blood & cancer
|v 64
|y 2017
|x 1545-5009
909 C O |p VDB
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910 1 _ |a Deutsches Krebsforschungszentrum
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