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000119391 041__ $$aeng
000119391 082__ $$a610
000119391 1001_ $$aAbbas, S.$$b0
000119391 245__ $$aDietary vitamin D intake and risk of type 2 diabetes in the European Prospective Investigation into Cancer and Nutrition: the EPIC-InterAct study.
000119391 260__ $$aNew York, NY$$bNature Publ. Group$$c2014
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000119391 520__ $$aProspective cohort studies have indicated that serum vitamin D levels are inversely related to risk of type 2 diabetes. However, such studies cannot determine the source of vitamin D. Therefore, we examined the association of dietary vitamin D intake with incident type 2 diabetes within the European Prospective Investigation into Cancer and Nutrition (EPIC)-InterAct study in a heterogeneous European population including eight countries with large geographical variation.Using a case-cohort design, 11,245 incident cases of type 2 diabetes and a representative subcohort (N=15,798) were included in the analyses. Hazard ratios (HR) and 95% confidence intervals (CIs) for type 2 diabetes were calculated using a Prentice-weighted Cox regression adjusted for potential confounders. Twenty-four-hour diet-recall data from a subsample (N=2347) were used to calibrate habitual intake data derived from dietary questionnaires.Median follow-up time was 10.8 years. Dietary vitamin D intake was not significantly associated with the risk of type 2 diabetes. HR and 95% CIs for the highest compared to the lowest quintile of uncalibrated vitamin D intake was 1.09 (0.97-1.22) (Ptrend=0.17). No associations were observed in a sex-specific analysis. The overall pooled effect (HR (95% CI)) using the continuous calibrated variable was 1.00 (0.97-1.03) per increase of 1 μg/day dietary vitamin D.This observational study does not support an association between higher dietary vitamin D intake and type 2 diabetes incidence. This result has to be interpreted in light of the limited contribution of dietary vitamin D on the overall vitamin D status of a person.
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000119391 650_7 $$01406-16-2$$2NLM Chemicals$$aVitamin D
000119391 7001_ $$aLinseisen, J.$$b1
000119391 7001_ $$aRohrmann, S.$$b2
000119391 7001_ $$aBeulens, J. W. J.$$b3
000119391 7001_ $$aBuijsse, B.$$b4
000119391 7001_ $$aAmiano, P.$$b5
000119391 7001_ $$aArdanaz, E.$$b6
000119391 7001_ $$aBalkau, B.$$b7
000119391 7001_ $$aBoeing, H.$$b8
000119391 7001_ $$aClavel-Chapelon, F.$$b9
000119391 7001_ $$aFagherazzi, G.$$b10
000119391 7001_ $$aFranks, P. W.$$b11
000119391 7001_ $$aGavrila, D.$$b12
000119391 7001_ $$aGrioni, S.$$b13
000119391 7001_ $$0P:(DE-He78)4b2dc91c9d1ac33a1c0e0777d0c1697a$$aKaaks, R.$$b14$$udkfz
000119391 7001_ $$aKey, T. J.$$b15
000119391 7001_ $$aKhaw, K. T.$$b16
000119391 7001_ $$0P:(DE-He78)0907a10ba1dc8f53f04907f54f6fdcfe$$aKühn, T.$$b17$$udkfz
000119391 7001_ $$aMattiello, A.$$b18
000119391 7001_ $$aMolina-Montes, E.$$b19
000119391 7001_ $$aNilsson, P. M.$$b20
000119391 7001_ $$aOvervad, K.$$b21
000119391 7001_ $$aQuirós, J. R.$$b22
000119391 7001_ $$aRolandsson, O.$$b23
000119391 7001_ $$aSacerdote, C.$$b24
000119391 7001_ $$aSaieva, C.$$b25
000119391 7001_ $$aSlimani, N.$$b26
000119391 7001_ $$aSluijs, I.$$b27
000119391 7001_ $$aSpijkerman, A. M. W.$$b28
000119391 7001_ $$aTjonneland, A.$$b29
000119391 7001_ $$aTumino, R.$$b30
000119391 7001_ $$avan der A, D. L.$$b31
000119391 7001_ $$aZamora-Ros, R.$$b32
000119391 7001_ $$aSharp, S. J.$$b33
000119391 7001_ $$aLangenberg, C.$$b34
000119391 7001_ $$aForouhi, N. G.$$b35
000119391 7001_ $$aRiboli, E.$$b36
000119391 7001_ $$aWareham, N. J.$$b37
000119391 773__ $$0PERI:(DE-600)2004986-9$$a10.1038/ejcn.2013.235$$gVol. 68, no. 2, p. 196 - 202$$n2$$p196 - 202$$tEuropean journal of clinical nutrition$$v68$$x1476-5640$$y2014
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