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@ARTICLE{Abbas:119391,
author = {S. Abbas and J. Linseisen and S. Rohrmann and J. W. J.
Beulens and B. Buijsse and P. Amiano and E. Ardanaz and B.
Balkau and H. Boeing and F. Clavel-Chapelon and G.
Fagherazzi and P. W. Franks and D. Gavrila and S. Grioni and
R. Kaaks$^*$ and T. J. Key and K. T. Khaw and T. Kühn$^*$
and A. Mattiello and E. Molina-Montes and P. M. Nilsson and
K. Overvad and J. R. Quirós and O. Rolandsson and C.
Sacerdote and C. Saieva and N. Slimani and I. Sluijs and A.
M. W. Spijkerman and A. Tjonneland and R. Tumino and D. L.
van der A and R. Zamora-Ros and S. J. Sharp and C.
Langenberg and N. G. Forouhi and E. Riboli and N. J.
Wareham},
title = {{D}ietary vitamin {D} intake and risk of type 2 diabetes in
the {E}uropean {P}rospective {I}nvestigation into {C}ancer
and {N}utrition: the {EPIC}-{I}nter{A}ct study.},
journal = {European journal of clinical nutrition},
volume = {68},
number = {2},
issn = {1476-5640},
address = {New York, NY},
publisher = {Nature Publ. Group},
reportid = {DKFZ-2017-00145},
pages = {196 - 202},
year = {2014},
abstract = {Prospective cohort studies have indicated that serum
vitamin D levels are inversely related to risk of type 2
diabetes. However, such studies cannot determine the source
of vitamin D. Therefore, we examined the association of
dietary vitamin D intake with incident type 2 diabetes
within the European Prospective Investigation into Cancer
and Nutrition (EPIC)-InterAct study in a heterogeneous
European population including eight countries with large
geographical variation.Using a case-cohort design, 11,245
incident cases of type 2 diabetes and a representative
subcohort (N=15,798) were included in the analyses. Hazard
ratios (HR) and $95\%$ confidence intervals (CIs) for type 2
diabetes were calculated using a Prentice-weighted Cox
regression adjusted for potential confounders.
Twenty-four-hour diet-recall data from a subsample (N=2347)
were used to calibrate habitual intake data derived from
dietary questionnaires.Median follow-up time was 10.8 years.
Dietary vitamin D intake was not significantly associated
with the risk of type 2 diabetes. HR and $95\%$ CIs for the
highest compared to the lowest quintile of uncalibrated
vitamin D intake was 1.09 (0.97-1.22) (Ptrend=0.17). No
associations were observed in a sex-specific analysis. The
overall pooled effect (HR $(95\%$ CI)) using the continuous
calibrated variable was 1.00 (0.97-1.03) per increase of
1 μg/day dietary vitamin D.This observational study does
not support an association between higher dietary vitamin D
intake and type 2 diabetes incidence. This result has to be
interpreted in light of the limited contribution of dietary
vitamin D on the overall vitamin D status of a person.},
keywords = {Vitamin D (NLM Chemicals)},
cin = {C020},
ddc = {610},
cid = {I:(DE-He78)C020-20160331},
pnm = {313 - Cancer risk factors and prevention (POF3-313)},
pid = {G:(DE-HGF)POF3-313},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:24253760},
pmc = {pmc:PMC4234029},
doi = {10.1038/ejcn.2013.235},
url = {https://inrepo02.dkfz.de/record/119391},
}