Home > Publications database > Dietary vitamin D intake and risk of type 2 diabetes in the European Prospective Investigation into Cancer and Nutrition: the EPIC-InterAct study. > print |
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024 | 7 | _ | |a 10.1038/ejcn.2013.235 |2 doi |
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024 | 7 | _ | |a 1476-5640 |2 ISSN |
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041 | _ | _ | |a eng |
082 | _ | _ | |a 610 |
100 | 1 | _ | |a Abbas, S. |b 0 |
245 | _ | _ | |a Dietary vitamin D intake and risk of type 2 diabetes in the European Prospective Investigation into Cancer and Nutrition: the EPIC-InterAct study. |
260 | _ | _ | |a New York, NY |c 2014 |b Nature Publ. Group |
336 | 7 | _ | |a article |2 DRIVER |
336 | 7 | _ | |a Output Types/Journal article |2 DataCite |
336 | 7 | _ | |a Journal Article |b journal |m journal |0 PUB:(DE-HGF)16 |s 1487316345_21592 |2 PUB:(DE-HGF) |
336 | 7 | _ | |a ARTICLE |2 BibTeX |
336 | 7 | _ | |a JOURNAL_ARTICLE |2 ORCID |
336 | 7 | _ | |a Journal Article |0 0 |2 EndNote |
520 | _ | _ | |a Prospective cohort studies have indicated that serum vitamin D levels are inversely related to risk of type 2 diabetes. However, such studies cannot determine the source of vitamin D. Therefore, we examined the association of dietary vitamin D intake with incident type 2 diabetes within the European Prospective Investigation into Cancer and Nutrition (EPIC)-InterAct study in a heterogeneous European population including eight countries with large geographical variation.Using a case-cohort design, 11,245 incident cases of type 2 diabetes and a representative subcohort (N=15,798) were included in the analyses. Hazard ratios (HR) and 95% confidence intervals (CIs) for type 2 diabetes were calculated using a Prentice-weighted Cox regression adjusted for potential confounders. Twenty-four-hour diet-recall data from a subsample (N=2347) were used to calibrate habitual intake data derived from dietary questionnaires.Median follow-up time was 10.8 years. Dietary vitamin D intake was not significantly associated with the risk of type 2 diabetes. HR and 95% CIs for the highest compared to the lowest quintile of uncalibrated vitamin D intake was 1.09 (0.97-1.22) (Ptrend=0.17). No associations were observed in a sex-specific analysis. The overall pooled effect (HR (95% CI)) using the continuous calibrated variable was 1.00 (0.97-1.03) per increase of 1 μg/day dietary vitamin D.This observational study does not support an association between higher dietary vitamin D intake and type 2 diabetes incidence. This result has to be interpreted in light of the limited contribution of dietary vitamin D on the overall vitamin D status of a person. |
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588 | _ | _ | |a Dataset connected to CrossRef, PubMed, |
650 | _ | 7 | |a Vitamin D |0 1406-16-2 |2 NLM Chemicals |
700 | 1 | _ | |a Linseisen, J. |b 1 |
700 | 1 | _ | |a Rohrmann, S. |b 2 |
700 | 1 | _ | |a Beulens, J. W. J. |b 3 |
700 | 1 | _ | |a Buijsse, B. |b 4 |
700 | 1 | _ | |a Amiano, P. |b 5 |
700 | 1 | _ | |a Ardanaz, E. |b 6 |
700 | 1 | _ | |a Balkau, B. |b 7 |
700 | 1 | _ | |a Boeing, H. |b 8 |
700 | 1 | _ | |a Clavel-Chapelon, F. |b 9 |
700 | 1 | _ | |a Fagherazzi, G. |b 10 |
700 | 1 | _ | |a Franks, P. W. |b 11 |
700 | 1 | _ | |a Gavrila, D. |b 12 |
700 | 1 | _ | |a Grioni, S. |b 13 |
700 | 1 | _ | |a Kaaks, R. |0 P:(DE-He78)4b2dc91c9d1ac33a1c0e0777d0c1697a |b 14 |u dkfz |
700 | 1 | _ | |a Key, T. J. |b 15 |
700 | 1 | _ | |a Khaw, K. T. |b 16 |
700 | 1 | _ | |a Kühn, T. |0 P:(DE-He78)0907a10ba1dc8f53f04907f54f6fdcfe |b 17 |u dkfz |
700 | 1 | _ | |a Mattiello, A. |b 18 |
700 | 1 | _ | |a Molina-Montes, E. |b 19 |
700 | 1 | _ | |a Nilsson, P. M. |b 20 |
700 | 1 | _ | |a Overvad, K. |b 21 |
700 | 1 | _ | |a Quirós, J. R. |b 22 |
700 | 1 | _ | |a Rolandsson, O. |b 23 |
700 | 1 | _ | |a Sacerdote, C. |b 24 |
700 | 1 | _ | |a Saieva, C. |b 25 |
700 | 1 | _ | |a Slimani, N. |b 26 |
700 | 1 | _ | |a Sluijs, I. |b 27 |
700 | 1 | _ | |a Spijkerman, A. M. W. |b 28 |
700 | 1 | _ | |a Tjonneland, A. |b 29 |
700 | 1 | _ | |a Tumino, R. |b 30 |
700 | 1 | _ | |a van der A, D. L. |b 31 |
700 | 1 | _ | |a Zamora-Ros, R. |b 32 |
700 | 1 | _ | |a Sharp, S. J. |b 33 |
700 | 1 | _ | |a Langenberg, C. |b 34 |
700 | 1 | _ | |a Forouhi, N. G. |b 35 |
700 | 1 | _ | |a Riboli, E. |b 36 |
700 | 1 | _ | |a Wareham, N. J. |b 37 |
773 | _ | _ | |a 10.1038/ejcn.2013.235 |g Vol. 68, no. 2, p. 196 - 202 |0 PERI:(DE-600)2004986-9 |n 2 |p 196 - 202 |t European journal of clinical nutrition |v 68 |y 2014 |x 1476-5640 |
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