%0 Journal Article
%A Gronych, Jan
%A Pfister, Stefan
%A Jones, David
%T Connect four with glioblastoma stem cell factors.
%J Cell
%V 157
%N 3
%@ 0092-8674
%C [Cambridge, Mass.]
%I Cell Press
%M DKFZ-2017-00743
%P 525 - 527
%D 2014
%X Hierarchical cell state models, wherein a few stem-like tumor-propagating cells repopulate the tumor after therapy, are often invoked in cancer. Suvà et al. demonstrate a plastic developmental hierarchy in glioma cell populations by characterizing the epigenetic states of phenotypically distinct cells and identifying four factors sufficient to reprogram differentiated cells into a tumorigenic stem-like state.
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:24766799
%R 10.1016/j.cell.2014.04.001
%U https://inrepo02.dkfz.de/record/120161