Journal Article (Review Article)

DKFZ-2017-00743

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Connect four with glioblastoma stem cell factors.

Gronych, J. (First author)DKFZ* ; Pfister, S.DKFZ* ; Jones, D. (Last author)DKFZ*

2014
Cell Press [Cambridge, Mass.]

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Please use a persistent id in citations: doi:10.1016/j.cell.2014.04.001

Abstract: Hierarchical cell state models, wherein a few stem-like tumor-propagating cells repopulate the tumor after therapy, are often invoked in cancer. Suvà et al. demonstrate a plastic developmental hierarchy in glioma cell populations by characterizing the epigenetic states of phenotypically distinct cells and identifying four factors sufficient to reprogram differentiated cells into a tumorigenic stem-like state.

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Contributing Institute(s):

1. Molekulare Genetik (B060)
2. Pädiatrische Neuroonkologie (B062)

Research Program(s):

1. 312 - Functional and structural genomics (POF3-312) (POF3-312)

Appears in the scientific report 2014

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Database coverage:
; BIOSIS Previews ; Current Contents - Life Sciences ; Ebsco Academic Search ; IF >= 25 ; JCR ; NCBI Molecular Biology Database ; Nationallizenz ; SCOPUS ; Science Citation Index ; Science Citation Index Expanded ; Thomson Reuters Master Journal List ; Web of Science Core Collection

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