TY - JOUR AU - Gronych, Jan AU - Pfister, Stefan AU - Jones, David TI - Connect four with glioblastoma stem cell factors. JO - Cell VL - 157 IS - 3 SN - 0092-8674 CY - [Cambridge, Mass.] PB - Cell Press M1 - DKFZ-2017-00743 SP - 525 - 527 PY - 2014 AB - Hierarchical cell state models, wherein a few stem-like tumor-propagating cells repopulate the tumor after therapy, are often invoked in cancer. Suvà et al. demonstrate a plastic developmental hierarchy in glioma cell populations by characterizing the epigenetic states of phenotypically distinct cells and identifying four factors sufficient to reprogram differentiated cells into a tumorigenic stem-like state. LB - PUB:(DE-HGF)16 C6 - pmid:24766799 DO - DOI:10.1016/j.cell.2014.04.001 UR - https://inrepo02.dkfz.de/record/120161 ER -