TY  - JOUR
AU  - Hünemohr, Nora
AU  - Krauss, Bernhard
AU  - Tremmel, Christoph
AU  - Ackermann, Benjamin
AU  - Jäkel, Oliver
AU  - Greilich, Steffen
TI  - Experimental verification of ion stopping power prediction from dual energy CT data in tissue surrogates.
JO  - Physics in medicine and biology
VL  - 59
IS  - 1
SN  - 1361-6560
CY  - Bristol
PB  - IOP Publ.
M1  - DKFZ-2017-02095
SP  - 83 - 96
PY  - 2014
AB  - We present an experimental verification of stopping-power-ratio (SPR) prediction from dual energy CT (DECT) with potential use for dose planning in proton and ion therapy. The approach is based on DECT images converted to electron density relative to water ϱe/ϱe, w and effective atomic number Zeff. To establish a parameterization of the I-value by Zeff, 71 tabulated tissue compositions were used. For the experimental assessment of the method we scanned 20 materials (tissue surrogates, polymers, aluminum, titanium) at 80/140Sn kVp and 100/140Sn kVp (Sn: additional tin filtration) and computed the ϱe/ϱe, w and Zeff with a purely image based algorithm. Thereby, we found that ϱe/ϱe, w (Zeff) could be determined with an accuracy of 0.4
KW  - Polymethyl Methacrylate (NLM Chemicals)
KW  - Aluminum (NLM Chemicals)
KW  - Titanium (NLM Chemicals)
LB  - PUB:(DE-HGF)16
C6  - pmid:24334601
DO  - DOI:10.1088/0031-9155/59/1/83
UR  - https://inrepo02.dkfz.de/record/125980
ER  -